To evaluate the relative efficacy of cisplatin, cyclophosphamide, and Adriamycin (doxorubicin;
Adria Laboratories, Columbus, OH) (CISCA) versus methotrexate, vinblastine, Adriamycin, …

Interleukin-7 (IL-7) is a homeostatic cytokine for resting T cells with increasing serum and
tissue levels during T cell depletion. In preclinical studies, IL-7 therapy exerts marked …

Background Prostate carcinoma is linked to osteoblasticmetastasis. We therefore investigated
the value of bonetargetedconsolidation therapy in selected patients with advanced …

Renal cell carcinoma is highly resistant to systemic chemotherapy, and no agent should be
considered standard in the treatment of metastatic disease. At this time, it is appropriate for …

Purpose: The TroVax Renal Immunotherapy Survival Trial was a randomized, placebo-controlled
phase III study that investigated whether modified vaccinia Ankara encoding the tumor …

BACKGROUND: Everolimus, an oral mammalian target of rapamycin (mTOR) inhibitor, affects
tumor growth by blocking growth factor stimulation, arresting cell cycle progression, and …

Purpose: Interleukin-7 (IL-7) has critical and nonredundant roles in T-cell development,
hematopoiesis, and postdevelopmental immune functions as a prototypic homeostatic cytokine. …

A total of 21 patients with metastatic small cell carcinoma of the prostate was treated with
combination chemotherapy, either following initial hormonal therapy (15) or as initial therapy (6)…

Quantitation of circulating tumor cells (CTCs) can provide information on the stage of a
malignancy, onset of disease progression and response to therapy. In an effort to more accurately …

99m Tc-EC20 is a folate receptor (FR)–targeted imaging agent consisting of the vitamin folate
conjugated to 99m Tc. FR is expressed on a variety of epithelial cancers, with advanced …