User profiles for Robert Ivkov
Robert IvkovThe Johns Hopkins University School of Medicine Verified email at jhmi.edu Cited by 7149 |
[HTML][HTML] Effect of magnetic dipolar interactions on nanoparticle heating efficiency: Implications for cancer hyperthermia
Nanostructured magnetic systems have many applications, including potential use in cancer
therapy deriving from their ability to heat in alternating magnetic fields. In this work we …
therapy deriving from their ability to heat in alternating magnetic fields. In this work we …
Application of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancer
R Ivkov, SJ DeNardo, W Daum, AR Foreman… - Clinical cancer …, 2005 - AACR
Objective: Magnetic nanoparticles conjugated to a monoclonal antibody can be iv injected
to target cancer tissue and will rapidly heat when activated by an external alternating …
to target cancer tissue and will rapidly heat when activated by an external alternating …
Development of Tumor Targeting Bioprobes (111In-Chimeric L6 Monoclonal Antibody Nanoparticles) for Alternating Magnetic Field Cancer Therapy
…, AR Foreman, C Gruettner, GN Adamson, R Ivkov - Clinical cancer …, 2005 - AACR
Objectives: 111 In-chimeric L6 (ChL6) monoclonal antibody (mAb)–linked iron oxide nanoparticle
(bioprobes) pharmacokinetics, tumor uptake, and the therapeutic effect of inductively …
(bioprobes) pharmacokinetics, tumor uptake, and the therapeutic effect of inductively …
Physics of heat generation using magnetic nanoparticles for hyperthermia
CL Dennis, R Ivkov - International Journal of Hyperthermia, 2013 - Taylor & Francis
Magnetic nanoparticle hyperthermia and thermal ablation have been actively studied
experimentally and theoretically. In this review, we provide a summary of the literature describing …
experimentally and theoretically. In this review, we provide a summary of the literature describing …
Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy's history, efficacy and application in humans
Hyperthermia therapy (HT) is the exposure of a region of the body to elevated temperatures
to achieve a therapeutic effect. HT anticancer properties and its potential as a cancer …
to achieve a therapeutic effect. HT anticancer properties and its potential as a cancer …
Heating technology for malignant tumors: A review
… Robert Ivkov is an inventor on nanoparticle patents. All patents are assigned to either The
Johns Hopkins University or Aduro BioTech, Inc. Robert Ivkov … Robert Ivkov also consults for …
Johns Hopkins University or Aduro BioTech, Inc. Robert Ivkov … Robert Ivkov also consults for …
[HTML][HTML] Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies
Significant research and preclinical investment in cancer nanomedicine has produced several
products, which have improved cancer care. Nevertheless, there exists a perception that …
products, which have improved cancer care. Nevertheless, there exists a perception that …
Thermal dosimetry predictive of efficacy of 111In-ChL6 nanoparticle AMF–induced thermoablative therapy for human breast cancer in mice
…, C Gruettner, GN Adamson, R Ivkov - Journal of Nuclear …, 2007 - Soc Nuclear Med
Antibody (mAb)-linked iron oxide nanoparticles (bioprobes) provide the opportunity to develop
tumor specific thermal therapy (Rx) for metastatic cancer when inductively heated by an …
tumor specific thermal therapy (Rx) for metastatic cancer when inductively heated by an …
Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer
The factors that influence nanoparticle fate in vivo following systemic delivery remain an area
of intense interest. Of particular interest is whether labeling with a cancer-specific antibody …
of intense interest. Of particular interest is whether labeling with a cancer-specific antibody …
Synthesis and antibody conjugation of magnetic nanoparticles with improved specific power absorption rates for alternating magnetic field cancer therapy
…, J Teller, F Westphal, A Foreman, R Ivkov - Journal of Magnetism …, 2007 - Elsevier
Bionized nanoferrite (BNF) particles with high specific power absorption rates were synthesized
in the size range of 20–100nm by high-pressure homogenization for targeted cancer …
in the size range of 20–100nm by high-pressure homogenization for targeted cancer …