User profiles for Robert Ivkov

Robert Ivkov

The Johns Hopkins University School of Medicine
Verified email at jhmi.edu
Cited by 7149

[HTML][HTML] Effect of magnetic dipolar interactions on nanoparticle heating efficiency: Implications for cancer hyperthermia

…, AS Costa, N Zufelato, MH Sousa, R Miotto, R Ivkov… - Scientific reports, 2013 - nature.com
Nanostructured magnetic systems have many applications, including potential use in cancer
therapy deriving from their ability to heat in alternating magnetic fields. In this work we …

Application of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancer

R Ivkov, SJ DeNardo, W Daum, AR Foreman… - Clinical cancer …, 2005 - AACR
Objective: Magnetic nanoparticles conjugated to a monoclonal antibody can be iv injected
to target cancer tissue and will rapidly heat when activated by an external alternating …

Development of Tumor Targeting Bioprobes (111In-Chimeric L6 Monoclonal Antibody Nanoparticles) for Alternating Magnetic Field Cancer Therapy

…, AR Foreman, C Gruettner, GN Adamson, R Ivkov - Clinical cancer …, 2005 - AACR
Objectives: 111 In-chimeric L6 (ChL6) monoclonal antibody (mAb)–linked iron oxide nanoparticle
(bioprobes) pharmacokinetics, tumor uptake, and the therapeutic effect of inductively …

Physics of heat generation using magnetic nanoparticles for hyperthermia

CL Dennis, R Ivkov - International Journal of Hyperthermia, 2013 - Taylor & Francis
Magnetic nanoparticle hyperthermia and thermal ablation have been actively studied
experimentally and theoretically. In this review, we provide a summary of the literature describing …

Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy's history, efficacy and application in humans

K Mahmoudi, A Bouras, D Bozec, R Ivkov… - International Journal …, 2018 - Taylor & Francis
Hyperthermia therapy (HT) is the exposure of a region of the body to elevated temperatures
to achieve a therapeutic effect. HT anticancer properties and its potential as a cancer …

Heating technology for malignant tumors: A review

…, W Ceelen, CL Brace, R Ivkov… - International Journal …, 2020 - Taylor & Francis
Robert Ivkov is an inventor on nanoparticle patents. All patents are assigned to either The
Johns Hopkins University or Aduro BioTech, Inc. Robert IvkovRobert Ivkov also consults for …

[HTML][HTML] Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies

…, P Korangath, D Serantes, S Fiering, R Ivkov - Advanced drug delivery …, 2020 - Elsevier
Significant research and preclinical investment in cancer nanomedicine has produced several
products, which have improved cancer care. Nevertheless, there exists a perception that …

Thermal dosimetry predictive of efficacy of 111In-ChL6 nanoparticle AMF–induced thermoablative therapy for human breast cancer in mice

…, C Gruettner, GN Adamson, R Ivkov - Journal of Nuclear …, 2007 - Soc Nuclear Med
Antibody (mAb)-linked iron oxide nanoparticles (bioprobes) provide the opportunity to develop
tumor specific thermal therapy (Rx) for metastatic cancer when inductively heated by an …

Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

…, W Fu, C Hu, S Sukumar, BW Simons, R Ivkov - Science …, 2020 - science.org
The factors that influence nanoparticle fate in vivo following systemic delivery remain an area
of intense interest. Of particular interest is whether labeling with a cancer-specific antibody …

Synthesis and antibody conjugation of magnetic nanoparticles with improved specific power absorption rates for alternating magnetic field cancer therapy

…, J Teller, F Westphal, A Foreman, R Ivkov - Journal of Magnetism …, 2007 - Elsevier
Bionized nanoferrite (BNF) particles with high specific power absorption rates were synthesized
in the size range of 20–100nm by high-pressure homogenization for targeted cancer …