[PDF][PDF] Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
…, L Zhang, X Zhao, G Xu, Y Zhang, AI Roberts, RC Zhao… - Cell stem cell, 2008 - cell.com
Mesenchymal stem cells (MSCs) can become potently immunosuppressive through unknown
mechanisms. We found that the immunosuppressive function of MSCs is elicited by IFNγ …
mechanisms. We found that the immunosuppressive function of MSCs is elicited by IFNγ …
Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo
…, Z Sun, L Liao, Y Meng, Q Han, RC Zhao - … and biophysical research …, 2005 - Elsevier
In this study, we isolated CD31 − , CD34 − , CD106 − (VCAM-1 − ), and fetal liver kinase + (Flk1
+ ) cells from adipose tissue. These cells can be induced to differentiate into cells of …
+ ) cells from adipose tissue. These cells can be induced to differentiate into cells of …
[HTML][HTML] Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia
…, H Li, Z Hu, F Zhang, J Gao, H Liu, X Li, Y Zhao… - Aging and …, 2020 - ncbi.nlm.nih.gov
A coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak
in Wuhan, China. Preventing and reversing the cytokine storm may be the key to save the …
in Wuhan, China. Preventing and reversing the cytokine storm may be the key to save the …
[HTML][HTML] Exosomes from mesenchymal stem/stromal cells: a new therapeutic paradigm
K Yin, S Wang, RC Zhao - Biomarker research, 2019 - Springer
Mesenchymal stem/stromal cells (MSCs) have been demonstrated to hold great potential for
the treatment of several diseases. Their therapeutic effects are largely mediated by …
the treatment of several diseases. Their therapeutic effects are largely mediated by …
[HTML][HTML] Clinical applications of mesenchymal stem cells
S Wang, X Qu, RC Zhao - Journal of hematology & oncology, 2012 - Springer
Mesenchymal stem cells (MSC) have generated a great amount of enthusiasm over the past
decade as a novel therapeutic paradigm for a variety of diseases. Currently, MSC based …
decade as a novel therapeutic paradigm for a variety of diseases. Currently, MSC based …
Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a
…, L Zhang, S Wang, Q Han, RC Zhao - Journal of cell …, 2016 - journals.biologists.com
… Xiaolei Liang, Lina Zhang, Shihua Wang, Qin Han, Robert Chunhua Zhao; Exosomes secreted
… Robert Chunhua Zhao conceived and designed the study, provided study material, and …
… Robert Chunhua Zhao conceived and designed the study, provided study material, and …
[HTML][HTML] Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice
…, L Liao, B Chen, B Li, L Chen, H Jia, RC Zhao - …, 2007 - haematologica.org
Background and Objectives The use of mesenchymal stem cells (MSC) for cell therapy
relies on the capacity of these cells to home and engraft long-term into the appropriate target …
relies on the capacity of these cells to home and engraft long-term into the appropriate target …
Systemic infusion of FLK1+ mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice
B Fang, M Shi, L Liao, S Yang, Y Liu, RC Zhao - Transplantation, 2004 - journals.lww.com
Background. Fibrosis is the common end stage of most liver diseases, for which, unfortunately,
there is no effective treatment available currently. It has been shown that mesenchymal …
there is no effective treatment available currently. It has been shown that mesenchymal …
[HTML][HTML] Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric …
…, W Zhou, J Li, Z Li, C Bai, L Zhao, Q Han, RC Zhao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: The protumor activities of cancer-associated fibroblasts (CAFs) suggest that
they are potential therapeutic targets for the treatment of cancer. The mechanism of CAF …
they are potential therapeutic targets for the treatment of cancer. The mechanism of CAF …
Exosomes from human adipose-derived mesenchymal stem cells promote migration through Wnt signaling pathway in a breast cancer cell model
R Lin, S Wang, RC Zhao - Molecular and cellular biochemistry, 2013 - Springer
Human mesenchymal stem cell (MSC)-conditioned medium (CM) was previously reported
to affect the biology of tumor cells; however, the precise mechanisms remain unclear. Here, …
to affect the biology of tumor cells; however, the precise mechanisms remain unclear. Here, …