[PDF][PDF] Fluorine-18-altanserin: a radioligand for the study of serotonin receptors with PET: radiolabeling and in vivo biologic behavior in rats
C Lemaire, R Cantineau, M Guillaume… - Journal of Nuclear …, 1991 - Soc Nuclear Med
MATERIALS AND METHODS StartingMaterials Most of the organic substratesand solvents
were of analytical grade from Aldrich. Methyl 2-isothiocyanatobenzoate, hydro bromic acid, …
were of analytical grade from Aldrich. Methyl 2-isothiocyanatobenzoate, hydro bromic acid, …
Serotonin 5HT2 Receptor Imaging in the Human Brain Using Positron Emission Tomography and a New Radioligand, [18F]Altanserin: Results in Young Normal …
…, M Guillaume, R Cantineau… - Journal of Cerebral …, 1995 - journals.sagepub.com
Changes in serotonin-2 receptors have been demonstrated in brain autopsy material from
patients with various neurodegenerative and affective disorders. It would be desirable to …
patients with various neurodegenerative and affective disorders. It would be desirable to …
A new route for the synthesis of [18F] fluoroaromatic substituted amino acids: no carrier added Lp-[18F] fluorophenylalanine
…, L Christiaens, AJ Palmer, R Cantineau - International Journal of …, 1987 - Elsevier
l -p-[ 18 F ] fluorophenylalanine was designed as a potential marker for probing protein
synthesis in the human brain by positron emission tomography. This radiotracer has been …
synthesis in the human brain by positron emission tomography. This radiotracer has been …
[PDF][PDF] No-carrier-added regioselective preparation of 6-[18F] fluoro-L-dopa
C Lemaire, M Guillaume, R Cantineau… - Journal of Nuclear …, 1990 - Soc Nuclear Med
The aminopolyether Kryptofix 222,(4, 7, 13, 16, 21, 24) hex aoxa-l, 10diazabicyclo [8.8.
81hexacosane, potassium carbon ate, and ethanol were obtained from Merck, Darmstadt, FRG. …
81hexacosane, potassium carbon ate, and ethanol were obtained from Merck, Darmstadt, FRG. …
Synthesis of 75Se‐2‐phenyl‐1,2‐benzisoselenazol‐3(2H)‐one (PZ 51; ebselen. A novel biologically active organo‐selenium compound
R Cantineau, G Tihange, A Plenevaux… - Journal of Labelled …, 1986 - Wiley Online Library
The preparation of 75 Se‐ebselen ( 75 Se‐PZ 51) in a high radiochemical yield (∼40 %)
and with a specific activity of 240 mCi/mM (8.9 GBq/mM) is described. It entails a very simple, …
and with a specific activity of 240 mCi/mM (8.9 GBq/mM) is described. It entails a very simple, …
An approach to the asymmetric synthesis of l-6-[18F] fluorodopa via NCA nucleophilic fluorination
C Lemaire, M Guillaume, R Cantineau… - International journal of …, 1991 - Elsevier
The NCA asymmetric synthesis of l-6-[ 18 F]fluorodopa starting from (1R,2R,5R)-[(+)-2-hydroxypinanyl-
3-idene]glycine t-butyl ester as chiral agent has been developed. After 18 F-…
3-idene]glycine t-butyl ester as chiral agent has been developed. After 18 F-…
Synthesis of fluorine-18 substituted aromatic aldehydes and benzyl bromides, new intermediates for nca [18F] fluorination
…, P Damhaut, A Plenevaux, R Cantineau… - International journal of …, 1992 - Elsevier
The synthesis of various [ 18 F]fluoroaromatic aldehydes using activated nitro precursors
and amino-polyether supported nucleophilic substitution with 18 F − is reported. These …
and amino-polyether supported nucleophilic substitution with 18 F − is reported. These …
Chemical processing for production of no-carrier-added selenium-73 from germanium and arsenic targets and synthesis of L-2-amino-4-([73Se] methylseleno) butyric …
…, C Brihaye, C Lemaire, R Cantineau - International journal of …, 1990 - Elsevier
The Ge( 4 He, xn) and 75 As(p, 3n) reactions were compared as the best potential routes for
routine production of selenium-73 ( 73 Se) for medical applications. With 26 MeV α particles, …
routine production of selenium-73 ( 73 Se) for medical applications. With 26 MeV α particles, …
Nucleophilic enantioselective synthesis of 6-[18F] fluoro-L-dopa via two chiral auxiliaries
C Lemaire, A Plenevaux, R Cantineau… - Applied Radiation and …, 1993 - Elsevier
Asymmetric nucleophilic synthesis of 6-[ 18 F]fluoro-l-dopa was investigated in order to
reach an enantiomeric excess of close to 100% of the l form of this amino acid. The …
reach an enantiomeric excess of close to 100% of the l form of this amino acid. The …
Quality assurance and quality control of short-lived radiopharmaceuticals for PET
…, SL Waters, B Långström, R Cantineau… - … for positron emission …, 1993 - Springer
General guidelines for the quality assurance and quality control of short-lived radiopharmaceuticals
for positron emission tomography (PET) are given. Quality assurance and quality …
for positron emission tomography (PET) are given. Quality assurance and quality …