[HTML][HTML] Role of genetic testing for inherited prostate cancer risk: Philadelphia Prostate Cancer Consensus Conference 2017

…, M Cooperberg, DE Crawford, RB Den… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this
conference was to develop an expert consensus-driven working framework for …

[HTML][HTML] Individual patient-level meta-analysis of the performance of the decipher genomic classifier in high-risk men after prostatectomy to predict development of …

…, K Yousefi, S Deheshi, AE Ross, RB Den… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose To perform the first meta-analysis of the performance of the genomic classifier test,
Decipher, in men with prostate cancer postprostatectomy. Methods MEDLINE, EMBASE, and …

Systematic review of hypofractionated radiation therapy for prostate cancer

…, N Ohri, TN Showalter, AP Dicker, RB Den - Cancer treatment …, 2013 - Elsevier
Prostate cancer is the second most prevalent solid tumor diagnosed in men in the United
States and Western Europe. Conventionally fractionated external beam radiation therapy (1.8–…

Implementation of germline testing for prostate cancer: Philadelphia Prostate Cancer Consensus Conference 2019

…, T Chandrasekar, DYT Chen, RB Den… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized multigene …

[HTML][HTML] Contemporary update of a multi-institutional predictive nomogram for salvage radiotherapy after radical prostatectomy

…, MS Anscher, D Moghanaki, RB Den… - Journal of clinical …, 2016 - scholarship.miami.edu
Purpose We aimed to update a previously published, multi-institutional nomogram of outcomes
for salvage radiotherapy (SRT) following radical prostatectomy (RP) for prostate cancer, …

A hormone–DNA repair circuit governs the response to genotoxic insult

…, RS Schrecengost, R de Leeuw, S Han, T Ma, RB Den… - Cancer discovery, 2013 - AACR
Alterations in DNA repair promote tumor development, but the impact on tumor progression
is poorly understood. Here, discovery of a biochemical circuit linking hormone signaling to …

Associations of luminal and basal subtyping of prostate cancer with prognosis and response to androgen deprivation therapy

…, MR Cooperberg, W Kim, CJ Ryan, RB Den… - JAMA …, 2017 - jamanetwork.com
Importance There is a clear need for a molecular subtyping approach in prostate cancer to
identify clinically distinct subgroups that benefit from specific therapies. Objectives To identify …

RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1

…, A Sahu, J Siddiqui, E Davicioni, RB Den… - The lancet …, 2014 - thelancet.com
Background Improved clinical predictors for disease progression are needed for localised
prostate cancer, since only a subset of patients develop recurrent or refractory disease after …

[HTML][HTML] Genomic classifier identifies men with adverse pathology after radical prostatectomy who benefit from adjuvant radiation therapy

RB Den, K Yousefi, EJ Trabulsi, F Abdollah… - Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Purpose The optimal timing of postoperative radiotherapy (RT) after radical prostatectomy (RP)
is unclear. We hypothesized that a genomic classifier (GC) would provide prognostic and …

Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis

…, RJ Karnes, AE Ross, EM Schaeffer, RB Den… - The lancet …, 2016 - thelancet.com
Background Postoperative radiotherapy has an important role in the treatment of prostate
cancer, but personalised patient selection could improve outcomes and spare unnecessary …