An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

…, KA Wilkinson, R Banchereau, J Skinner, RJ Wilkinson… - Nature, 2010 - nature.com
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …

[HTML][HTML] T cell responses to SARS-CoV-2 spike cross-recognize Omicron

…, A Grifoni, D Weiskopf, A Sette, RJ Wilkinson… - Nature, 2022 - nature.com
The SARS-CoV-2 Omicron variant (B.1.1.529) has multiple spike protein mutations 1 , 2 that
contribute to viral escape from antibody neutralization 3 , 4 , 5 – 6 and reduce vaccine …

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

…, JA Flynn, D Schnappinger, RJ Wilkinson… - Nature Reviews …, 2009 - nature.com
Immunological tests provide evidence of latent tuberculosis in one third of the global population,
which corresponds to more than two billion individuals. Latent tuberculosis is defined by …

The immune response in tuberculosis

…, FW McNab, CI Bloom, RJ Wilkinson… - Annual review of …, 2013 - annualreviews.org
There are 9 million cases of active tuberculosis reported annually; however, an estimated
one-third of the world's population is infected with Mycobacterium tuberculosis and remains …

Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study

RJ Wilkinson, M Llewelyn, Z Toossi, P Patel, G Pasvol… - The Lancet, 2000 - thelancet.com
Robert Wilkinson and Robert Davidson had the idea for the study and supervised its design,
execution, and analysis. Martin Llewelyn and Robert Wilkinson … Patel, Robert Wilkinson, and …

Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade

…, E Poon, M Morrow, R Stewart, H Jones, RW Wilkinson… - Cancer research, 2014 - AACR
Radiotherapy is a major part in the treatment of most common cancers, but many patients
experience local recurrence with metastatic disease. In evaluating response biomarkers, we …

Tuberculous meningitis: a uniform case definition for use in clinical research

…, K Prasad, PR Donald, RJ Wilkinson… - The Lancet infectious …, 2010 - thelancet.com
Tuberculous meningitis causes substantial mortality and morbidity in children and adults.
More research is urgently needed to better understand the pathogenesis of disease and to …

Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

…, JH Elliott, D Murdoch, RJ Wilkinson… - The Lancet infectious …, 2008 - thelancet.com
The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important
early complication of antiretroviral therapy (ART) in resource-limited settings, especially in …

[PDF][PDF] Some clinical considerations in the prevention of suicide based on a study of 134 successful suicides

…, GE Murphy, RH Wilkinson Jr… - … Journal of Public …, 1959 - ajph.aphapublications.org
SOME CLINICAL CONSIDERATIONS IN THE PREVENTION Page 1 A study of suicides that
succeeded shows that the majority were mentally ill. The individuals concerned suffered from …

High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

…, CM Rutterford, CA Mein, GR Davies, RJ Wilkinson… - The Lancet, 2011 - thelancet.com
Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of …