Microparticles are small membrane vesicles that are released from cells upon activation or
during apoptosis. Cellular microparticles in body fluids constitute a heterogeneous population…

Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into their
environment. Why do cells release vesicles? Initial studies showed that eukaryotic vesicles …

Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …

Deficiency of early components of the classical pathway of complement, particularly C1q,
predisposes to the development of systemic lupus erythematosus. Several studies have …

Background Isolation of extracellular vesicles from plasma is a challenge due to the presence
of proteins and lipoproteins. Isolation of vesicles using differential centrifugation or density-…

Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological
conditions, the interest in EVs is exponentially growing. EVs hold high hopes for novel …

We determined the numbers, cellular origin and thrombin-generating properties of microparticles
in healthy individuals (n = 15). Micro-particles, isolated from fresh blood samples and …

Patients with meningococcal sepsis generally suffer from disseminated intravascular
coagulation (DIC). The aim of this study was to address whether these patients have elevated …

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐consensus
rigour initiative of the International Society for Extracellular Vesicles (ISEV). The last …