Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

…, S Aratani, H Fujita, L Zhang, R Ikeda… - Genes & …, 2003 - genesdev.cshlp.org
Rheumatoid arthritis (RA) is one of the most critical articular diseases with synovial
hyperplasia followed by impairment of quality of life. However, the mechanism(s) that regulates …

Cytoplasmic destruction of p53 by the endoplasmic reticulum‐resident ubiquitin ligase 'Synoviolin'

…, T Yamadera, E Bae, S Toriyama, R Ikeda… - The EMBO …, 2007 - embopress.org
Synoviolin, also called HRD1, is an E3 ubiquitin ligase and is implicated in endoplasmic
reticulum ‐associated degradation. In mammals, Synoviolin plays crucial roles in various …

Analytical methods for abused drugs in hair and their applications

M Wada, R Ikeda, N Kuroda, K Nakashima - Analytical and bioanalytical …, 2010 - Springer
Hair has been focused on for its usability as an alternative biological specimen to blood and
urine for determining drugs of abuse in fields such as forensic and toxicological sciences …

Simple HPLC‐UV determination of nucleosides and its application to the authentication of Cordyceps and its allies

R Ikeda, M Nishimura, Y Sun, M Wada… - Biomedical …, 2008 - Wiley Online Library
A simple HPLC‐UV method combined with a simple extraction procedure of nucleosides (adenosine,
cordycepin, 2′‐deoxyadenosine, guanosine and uridine) was developed and …

A simple HPLC-fluorescence method for quantitation of curcuminoids and its application to turmeric products

J Zhang, S Jinnai, R Ikeda, M Wada, S Hayashidac… - Analytical …, 2009 - Springer
An HPLC method using fluorescence detection for the quantitation of curcuminoids, such as
curcumin (C), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) in turmeric …

[HTML][HTML] Efficacy of superselective conventional transarterial chemoembolization using guidance software for hepatocellular carcinoma within three lesions smaller …

S Miyayama, M Yamashiro, R Ikeda, J Matsumoto… - Cancers, 2021 - mdpi.com
Simple Summary Although transarterial chemoebolization (TACE) is indicated for small
hepatocellular carcinoma (HCC) as a second choice, TACE for small HCC is frequently difficult …

Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

R Ikeda, M Yanagisawa, N Takahashi… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Background Previous reports suggest that Brazilian propolis has multiple biological functions
and may help to restore adiponectin expression and insulin sensitivity. However, little is …

Quantification of coumarin derivatives in Noni (Morinda citrifolia) and their contribution of quenching effect on reactive oxygen species

R Ikeda, M Wada, T Nishigaki, K Nakashima - Food Chemistry, 2009 - Elsevier
The quantification of coumarin derivatives such as scopoletin, 7-hydroxycoumarin (7-HC)
and 4-hydroxycoumarin (4-HC) in Noni (Morinda citrifolia) was described. The coumarin …

Outcomes of patients with hepatocellular carcinoma treated with conventional transarterial chemoembolization using guidance software

S Miyayama, M Yamashiro, N Sugimori, R Ikeda… - Journal of Vascular and …, 2019 - Elsevier
Purpose To evaluate the outcomes of conventional transarterial chemoembolization using
guidance software for hepatocellular carcinoma (HCC) patients. Materials and Methods One …

Safety and effectiveness of empagliflozin in Japanese patients with type 2 diabetes: interim analysis from a post-marketing surveillance study

K Kaku, R Chin, Y Naito, H Iliev, R Ikeda… - Expert Opinion on …, 2020 - Taylor & Francis
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors are effective treatments for
type 2 diabetes mellitus (T2DM). We present the interim findings of an ongoing post-…