Purpose To explore and evaluate the potential value of dynamic contrast-enhanced (DCE)
magnetic resonance imaging (MRI) for the prediction of pathologic response to neoadjuvant …

Germline CDH1 mutations confer a high lifetime risk of developing diffuse gastric (DGC) and
lobular breast cancer (LBC). A multidisciplinary workshop was organised to discuss genetic …

Background: The standard curative treatment for patients with esophageal cancer is
perioperative chemotherapy or preoperative chemoradiotherapy followed by open transthoracic …

Purpose: The CROSS trial established neoadjuvant chemoradiotherapy (nCRT) for patients
with resectable esophageal adenocarcinoma (rEAC). In the PERFECT trial, we investigated …

Background Treatment of patients with ileocaecal Crohn's disease who have not responded
to conventional therapy is commonly scaled up to biological agents, but surgery can also …

Background Transthoracic esophagectomy with extended lymph node dissection is associated
with higher morbidity rates than transhiatal esophagectomy. This morbidity rate could be …

Background After neoadjuvant chemoradiotherapy for oesophageal cancer, roughly half of
the patients with squamous cell carcinoma and a quarter of those with adenocarcinoma have …

Background The possible advantages of laparoscopic (assisted) total gastrectomy (LTG)
versus open total gastrectomy (OTG) have not been reviewed systematically. The aim of this …

METHODS In 10 experienced upper GI centers in the Netherlands, patients with resectable (cT1-4aN0-3bM0)
gastric adenocarcinoma were randomly assigned to either laparoscopic or …

Background In 2011, the Dutch Upper Gastrointestinal Cancer Audit (DUCA) group began
nationwide registration of all patients undergoing surgery with the intention of resection for …