The objective of this work was the preclinical evaluation of"" Tc-P280, a""" Tc-labeled
peptide having high affinity and specificity for the GPIIb/llla receptor expressed on activated …

[DTPAjoctreotide. Conclusion: The high SSTR-binding affinity and high, receptor-specific
and saturable in vivo tumor uptake indicate that"" Tc-PSS? and 99mTc-P829 are promising …

The synthesis of peptides which possess a high affinity for the somatostatin receptor and
contain a chelator for the radionuclide technetium-99m is described. The target compounds …

Somatostatin derivative peptides previously designed for radiodiagnostic purposes ( 99m
Tc P829 or 99m Tc depreotide) were reoptimized for radiotherapy of tumors with rhenium …

Bifunctional chelators for labeling antibodies with 99mTc based on the N3S core of (mercaptoacetyl)-triglycine
having ester or amide linking moieties were synthesized and site-…

Murine monoclonal antimyosin antibody has been shown experimentally to bind selectively
to irreversibly damaged myocytes. To evaluate the safety and efficacy of monoclonal …

Platelet-specific compounds which are radiolabeled with γ-emitting radionuclides may be
particularly useful for the noninvasive in vivo detection of thrombi. The synthesis of peptides …

Our method is based on the frequently reported observation that acid chlorides of-tertiary
amino acids are unstable. These observations were first rationalized by Maksimov6 who …

A series of bis (arene) technetium (I) complexes has been synthesized from" mTc04-in order
to study their organ distribution. Syntheses using either ultrasound/Al/A1C13 or Zn/HCl …

(Dvi). The goalOfthis studywas to evaluatedinically@ 7c-P280 for ima@ ngDVT. The peptide
P280 is a 26 amino acid dimerthatbindswithhighaffinitytotheGPlIbIlllareceptorex pressedon …