We are developing a self-assembling non-viral in vivo gene delivery vehicle based on poly-l-lysine
and plasmid DNA. We have characterized poly-l-lysines of different chain lengths for …

Because monoclonal antibodies can recognize and bind to specific groups of atoms such
as tumour antigens, they have promise for use in vivo as carriers of radionuclides, drugs or …

Therapeutic vaccination using T‐cell receptor (TCR) peptides from V genes commonly
expressed by potentially pathogenic T cells remains an approach of interest for treatment of …

Advances in clinical immunodiagnostics resulting from the application of hybridoma technology
are starting to appear. Monoclonal antibodies are beginning to displace their antiquated …

Moloney leukemia virus activated both the classical and alternative pathways of human
complement. About 500,000 virions were required to detect activation of the classical pathway …

Studies were performed to determine the effect of tumor size on the incorporation of radiolabeled
monoclonal antftumor anlibodies (MoAbs) into human tumors growing in nude mice. …

Monoclonal antibodies (MoAbs) against carcinoembryonic antigen were successfully
radiolabeled with 111 In, and the radiopharmaceutical was characterized in vitro and in normal …

8 phytoestrogens were tested for mutagenicity using a variation of the Salmonella/mammalian
microsome (or Ames) assay. Zearalenone is a mycotoxin produced by a grain contaminant…

A radiolabeled monoclonal antibody (96.5) reactive with an M r 97,000 antigen found on
over 80% of melanoma cell lines and tissue extracts was examined for its ability to detect …

The purpose of this study was to determine the safety, toxicity, and antitumor immune
response following SC immunizations with a mixture of irradiated, autologous tumor cells and …