We analyzed prospectively 1213 adults with de novo acute myeloid leukemia (AML) to
ascertain the prognostic impact of cytogenetic abnormalities on complete remission (CR) rate, 5-…

The goal of this phase II multicenter clinical trial was to evaluate a new intensive chemotherapy
program for adults with untreated acute lymphoblastic leukemia (ALL) and to examine …

Background and purpose: To evaluate the long term clinical significance of tumor oxygenation
in a population of head and neck cancer patients receiving radiotherapy and to assess …

Background Elderly patients with primary acute myelogenous leukemia (AML) are less likely
to enter remission than younger adults, in part because of a higher mortality rate related to …

The Cancer and Leukemia Group B conducted a phase 3 trial of the P-glycoprotein modulator
PSC-833 in untreated acute myeloid leukemia patients aged 60 years and older. Patients …

We studied the risk of the development of acute myeloid leukemia (AML) during initial remission
in 733 consecutive children with acute lymphoid leukemia (ALL) who were treated with …

Mutation of the PTEN tumor suppressor gene is a frequent event in endometrial cancers. In
other types of cancers, PTEN mutation has been associated with metastatic behavior and …

PURPOSE: To examine the effect of single compared with repetitive (at least three) cycles of
high-dose cytarabine after induction therapy for patients with acute myeloid leukemia (AML) …

The Cancer and Leukemia Group B (CALGB) has been conducting a prospective cytogenetic
companion study (CALGB 8461) to all CALGB treatment protocols for newly diagnosed …

The Philadelphia (Ph1) chromosome, or its molecular counterpart, the BCR-ABL fusion gene,
is a rare but important prognostic indicator in childhood acute lymphoblastic leukemia (ALL…