It has been hypothesized on the basis of animal models of epilepsy that abnormal neural
activity in epilepsy may be related to reorganized neural circuits that facilitate epileptogenesis. …

Recent studies have provided new information regarding the optimal surveillance protocols
for low-risk patients with differentiated thyroid cancer (DTC). This article summarizes the …

Context/Objective: Approximately 15% of thyroid cancer patients develop subsequent metastases.
The clinical course of patients with metastatic thyroid carcinoma is highly variable. We …

Background. Parkinson's disease is characterized by the loss of midbrain dopamine
neurons that innervate the caudate and the putamen. Studies in animals suggest that fetal …

The effectiveness of bromocriptine in reducing tumor size has not been evaluated
systematically, nor has its use as primary therapy for prolactin-secreting macroadenomas been …

AGING is a multifactorial process that results in heterogeneous patterns of progressive morbidity
and disability (1–3). This complex process is influenced by multiple internal homeostatic …

Poorly differentiated thyroid cancer lesions often lose the ability to concentrate radioactive [
131 I]iodine (RAI) and exhibit increased metabolic activity, as evidenced by enhanced …

Compared with conventional, whole-organ, S-factor-based dosimetry, 3-dimensional (3D),
patient-specific dosimetry better accounts for radionuclide distribution and anatomic patient …

Progressive dedifferentiation of thyroid cancer cells leads to a loss of iodine-concentrating
ability, with resultant false negative, whole body radioactive iodine scans in approximately 20…

The use of radioactive iodine ( 131 I) for the treatment of thyroid carcinoma has changed
over the past 50 y. These changes are based on increasing awareness of the biophysical …