Background Brain metastases are common in human epidermal growth factor receptor (Her)-2-positive
breast cancer. Drug access to brain metastases and normal brain is key to …

• The potential utility of circulating tumor DNA (ctDNA) to detect minimal residual disease (MRD)
following surgery and/or adjuvant therapy and to monitor metastatic disease has been …

We report the safety, biodistribution, and internal radiation dosimetry of a new PET tracer,
18 F-AH111585, a peptide with a high affinity for the α v β 3 integrin receptor involved in …

CDK7 inhibition has emerged as a promising strategy in a range of cancer indications. CDK7
acts as a regulator of transcription through its role in phosphorylating and activating RNA …

Triple-negative breast cancer (TNBC) is a highly aggressive and heterogeneous subtype of
breast cancer that commonly exhibit poor prognosis and high relapse rates at early stages …

Since publication of their article [1], the authors have become aware that there is an error in
the description of the image data in the legend to Fig. 5. The second sentence of the legend …

Background: [ 18 F]ICMT-11 is an isatin analogue which has been developed by our group
as a novel PET radiotracer for studies of apoptosis in vivo. Preclinical studies have …

… Guttery, Simak Ali, Raoul C. Coombes. Circulating tumor DNA for early detection and
intervention in breast cancer: ctDNA profiles discriminate between healthy women in a true cancer …

… Raoul C. Coombes declares that he has no conflict of interest. Otavia L. Caballero declares
… Caballero OL, Shousha S, Zhao Q, Simpson AJ, Coombes RC, Neville AM. Expression of …

Purpose: Up to 30% of patients with breast cancer relapse after primary treatment. There
are no sensitive and reliable tests to monitor these patients and detect distant metastases …