User profiles for Ranjan Duara

Ranjan Duara

Medical Director, Wien Center for Alzheimer's Disease and Memory Disorders
Verified email at msmc.com
Cited by 40702

Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial

…, S Dixit, J Dobryniewski, R Drake, P Drysdale, R Duara… - Jama, 2023 - jamanetwork.com
Importance There are limited efficacious treatments for Alzheimer disease. Objective To assess
efficacy and adverse events of donanemab, an antibody designed to clear brain amyloid …

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

…, L Pinessi, I Rainero, S Sorbi, A Bruni, R Duara… - Nature …, 2007 - nature.com
The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic
pathways plays a key role in the generation of amyloid β peptide (Aβ) in Alzheimer disease. …

TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

…, D Personett, P Davies, R Duara… - Annals of Neurology …, 2007 - Wiley Online Library
Objective This study aimed to determine the frequency of frontotemporal lobar degeneration
with ubiquitinated inclusions (FTLD‐U) in the setting of hippocampal sclerosis (HpScl) and …

Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study

…, OA Ross, RC Petersen, R Duara… - The Lancet …, 2011 - thelancet.com
Background Neurofibrillary pathology has a stereotypical progression in Alzheimer's disease
(AD) that is encapsulated in the Braak staging scheme; however, some AD cases are …

Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank

…, B Robinson, G Pearl, D Dickson, R Duara - Alzheimer Disease & …, 2002 - journals.lww.com
Alzheimer disease (AD) is the most common dementing illness in the elderly, but there is
equivocal evidence regarding the frequency of other disorders such as Lewy body disease (…

Depression as a risk factor for Alzheimer disease: the MIRAGE Study

…, S Auerbach, R Go, D Sadovnick, R Duara… - Archives of …, 2003 - jamanetwork.com
Background Depression symptoms may be associated with the development of Alzheimer
disease (AD). Objectives To evaluate the association between depression symptoms and risk …

Positron emission tomography in Alzheimer's disease

R Duara, C Grady, J Haxby, M Sundaram, NR Cutler… - Neurology, 1986 - AAN Enterprises
Twenty-one patients with a clinical diagnosis of dementia of the Alzheimer's type (DAT) and
29 healthy, age-matched controls were studied using positron emission tomography (PET) …

A new scale for the assessment of functional status in Alzheimer's disease and related disorders

DA Loewenstein, E Amigo, R Duara… - Journal of …, 1989 - academic.oup.com
Assessment of the functional competencies of patients with dementia is typically conducted
in an indirect manner. Psychological tests of cognition or descriptions by relatives or other …

Cerebral metabolic effects of a verbal fluency test: A PET scan study

…, A Apicella, WA Sheramata, R Duara - Journal of clinical and …, 1988 - Taylor & Francis
Sixteen normal volunteers were studied with [F-18] fluorodeoxyglucose and positron emission
tomography scans during behavioral activation with a verbal fluency test, and 35 age-…

Mild cognitive impairment: directions for future research

…, DA Loewenstein, A Acevedo, WW Barker, R Duara - Neurology, 2003 - AAN Enterprises
Mild cognitive impairment (MCI), an intermediate state between normal aging and dementia,
is characterized by acquired cognitive deficits, without significant decline in functional …