User profiles for Ramesh Mukkamala
Ramesh MukkamalaAssociate Research Scientist, Purdue university Verified email at purdue.edu Cited by 210 |
Design and characterization of fibroblast activation protein targeted pan-cancer imaging agent for fluorescence-guided surgery of solid tumors
Tumor-targeted fluorescent dyes have been shown to significantly improve a surgeon's
ability to locate and resect occult malignant lesions, thereby enhancing a patient's chances of …
ability to locate and resect occult malignant lesions, thereby enhancing a patient's chances of …
[HTML][HTML] Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents
Background: Cancer-associated fibroblasts (CAFs) comprise a major cell type in the tumor
microenvironment where they support tumor growth and survival by producing extracellular …
microenvironment where they support tumor growth and survival by producing extracellular …
Synthesis of Benzyl C‐Analogues of Dapagliflozin as Potential SGLT2 Inhibitors
R Mukkamala, R Kumar, SK Banerjee… - European Journal of …, 2020 - Wiley Online Library
Sodium‐glucose co‐transporter (SGLT) inhibitors are a novel class of therapeutic agents for
the treatment of type 2 diabetes based on blocking of renal reabsorption of glucose. …
the treatment of type 2 diabetes based on blocking of renal reabsorption of glucose. …
Exploring the role of the spacers and acceptors on the triphenylamine-based dyes for dye-sensitized solar cells
Six triphenylamine-based dyes were explored for their application in dye-sensitized solar cells
(DSSCs). Dyes 1–3 and dyes 4–6 possess cyanoacrylic acid (C-acceptor) and rhodanine-…
(DSSCs). Dyes 1–3 and dyes 4–6 possess cyanoacrylic acid (C-acceptor) and rhodanine-…
Metal-free bipolar/octupolar organic dyes for DSSC application: A combined experimental and theoretical approach
This study evaluated four donor-π-linker-acceptor (D-π-A) dyes experimentally, which either
have 1 or 3 triphenylamine (TPA) donor in combination with either pyridine or N-methyl …
have 1 or 3 triphenylamine (TPA) donor in combination with either pyridine or N-methyl …
Fibroblast activation protein–targeted radioligand therapy for treatment of solid tumors
SD Lindeman, R Mukkamala, A Horner… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Fibroblast activation protein (FAP) has received increasing attention as an oncologic target
because of its prominent expression in solid tumors but virtual absence from healthy tissues. …
because of its prominent expression in solid tumors but virtual absence from healthy tissues. …
A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors
IS Aidhen, R Mukkamala, C Weidner, S Sauer - Organic letters, 2015 - ACS Publications
A common building block for the synthesis of amorfrutin and cajaninstilbene acid derivatives
has been developed. The library of synthesized compounds has enabled identification of …
has been developed. The library of synthesized compounds has enabled identification of …
Nanoparticles Targeted to Fibroblast Activation Protein Outperform PSMA for MRI Delineation of Primary Prostate Tumors
Accurate delineation of gross tumor volumes remains a barrier to radiotherapy dose escalation
and boost dosing in the treatment of solid tumors, such as prostate cancer. Magnetic …
and boost dosing in the treatment of solid tumors, such as prostate cancer. Magnetic …
Iodine‐Promoted Oxidative Conversion of o‐Vinyl Diaryl Ketones into o‐Acetyl Diaryl Ketones, Synthesis of 1‐Methyl‐4‐arylphthalazines as Analogues of …
K Harikrishna, R Mukkamala… - European Journal of …, 2014 - Wiley Online Library
A new method is described for the metal‐free oxidation of o‐vinyl diaryl ketones in the
presence of molecular iodine or N‐iodosuccinimide to give o‐acetyl diaryl ketones. This …
presence of molecular iodine or N‐iodosuccinimide to give o‐acetyl diaryl ketones. This …
Convenient Access to Acyl‐Substituted Bis (styrylbenzenes) Based on Building Blocks Using Julia Olefination and Weinreb Amide Chemistry
R Mukkamala, A Senthilmurugan… - European Journal of …, 2013 - Wiley Online Library
In an effort to arrive at bis(styrylbenzene) derivatives, which are known for their importance
in connection to Alzheimer's disease, two bifunctional building blocks that enable a C–C …
in connection to Alzheimer's disease, two bifunctional building blocks that enable a C–C …