Effects of intravenous glucose on dopaminergic function in the human brain in vivo

LT Haltia, JO Rinne, H Merisaari, RP Maguire… - Synapse, 2007 - Wiley Online Library
Dopamine is known to regulate food intake by modulating food reward via the mesolimbic
circuitry of the brain. The objective of this study was to compare the effects of high energy input …

A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy …

…, S Henry, H Gao, R Pracitto, RP Maguire… - …, 2019 - Wiley Online Library
Objective Brivaracetam (BRV) and levetiracetam (LEV) are antiepileptic drugs that bind
synaptic vesicle glycoprotein 2A (SV2A). In vitro and in vivo animal studies suggest faster brain …

Cerebral glucose metabolism in patients with spasmodic torticollis

…, A Antonini, U Roelcke, RP Maguire… - … : official journal of the …, 1997 - Wiley Online Library
The pathophysiology of spasmodic torticollis is not clear. Basal ganglia dysfunction has
been suggested to underlie this clinical syndrome. We studied resting cerebral glucose …

Imaging Brain Tumor Proliferative Activity with [124I]Iododeoxyuridine

…, NEA Crompton, P Vontobel, J Missimer, RP Maguire… - Cancer Research, 2000 - AACR
Iododeoxyuridine (IUdR) uptake and retention was imaged by positron emission tomography
(PET) at 0–48 min and 24 h after administration of 28.0–64.4 MBq (0.76–1.74 mCi) of[ 124 I]…

Effects of high amphetamine dose on mood and cerebral glucose metabolism in normal volunteers using positron emission tomography (PET)

FX Vollenweider, RP Maguire, KL Leenders… - Psychiatry Research …, 1998 - Elsevier
The effects of high euphorigenic doses of d-amphetamine (0.9–1.0 mg/kg po) on regional
cerebral glucose metabolism (rCMRglu) and psychological measures were investigated in 10 …

PET imaging drug distribution after intratumoral injection: the case for 124I-iododeoxyuridine in malignant gliomas

…, J Missimer, RP Maguire, P Freitag… - Journal of Nuclear …, 2002 - Soc Nuclear Med
Locoregional administration may yield higher tumor drug concentrations compared with
intravenous injection and may reduce the risk of systemic adverse effect. Furthermore, in the …

Striatal FDOPA uptake and cognition in advanced non-demented Parkinson's disease: a clinical and FDOPA-PET study

…, AT Portman, HAL Kiers, RP Maguire… - Parkinsonism & related …, 2008 - Elsevier
This study sought to determine the nature of the relationship between cognition and striatal
dopaminergic functioning in 28 patients with advanced Parkinson's disease (PD) using …

[PDF][PDF] Dexamethasone treatment and plasma glucose levels: relevance for fluorine-18-fluorodeoxyglucose uptake measurements in gliomas

…, S Hofer, P Vontobel, RP Maguire… - Journal of Nuclear …, 1998 - Soc Nuclear Med
MATERIALS AND METHODS FDG PET data from 19 patients with histologically proven
supratentorial malignant gliomas were analyzed retrospectively. Fifteen patients (aged 53 Ā±12 …

[HTML][HTML] Regional brain mGlu5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers

…, A Buck, SM Ametamey, M Blagoev, RP Maguire… - NeuroImage, 2021 - Elsevier
Mavoglurant binds to same allosteric site on metabotropic glutamate receptor 5 (mGluR5) as
[ 11 C]-ABP688, a radioligand. This open-label, single-center pilot study estimates extent of …

Functional magnetic resonance imaging of brightness induction in the human visual cortex

CC Boucard, JJ van Es, RP Maguire… - …, 2005 - journals.lww.com
A grey surface on a bright background appears to be darker than the same surface on a dark
background. We used functional magnetic resonance imaging to study this phenomenon …