Cell-to-cell communication is a crucial prerequisite for the development and maintenance of
multicellular organisms. To date, diverse mechanisms of intercellular exchange of …

Mesenchymal stem cells (MSC) comprise a promising tool for cellular therapy. These cells
are usually culture expanded prior to their application. However, a precise molecular …

Ectopic expression of Myc induces Cdk2 kinase activity in quiescent cells and antagonizes
association of p27 kip1 with Cdk2. The target gene (s) by which Myc mediates this effect is …

The two MAP kinases JNK and ERK direct distinct cellular activities even though they share
a number of common substrates, including several transcription factors. Here we have …

Cdc25 phosphatases play key roles in cell cycle progression by activating cyclin-dependent
kinases. In human cells, cdc25 proteins are encoded by a multigene family, consisting of …

A new approach is presented which allows the in vivo visualization of individual chromosome
territories in the nuclei of living human cells. The fluorescent thymidine analog Cy3-AP3-…

The involvement of α v β 3 and α v β 5 integrins in angiogenesis and the use of integrin
antagonists as effective antiangiogenic agents are documented. Radiotherapy is an important …

Importin β-type transport receptors mediate the vast majority of transport pathways between
cell nucleus and cytoplasm. We identify here the translation elongation factor 1A (eEF1A) as …

OBJECTIVE: Mesenchymal stem cells (MSC) raise high hopes in clinical applications. However,
the lack of common standards and a precise definition of MSC preparations remains a …

Mesenchymal stromal cells (MSC) have been suggested to provide a suitable cellular
environment for in vitro expansion of haematopoietic stem and progenitor cells (HPC) from …