Purpose An objective of the fifth National Wilms' Tumor Study (NWTS-5) was to evaluate the
efficacy of treatment regimens for anaplastic histology Wilms' tumor (AH).

p53-dependent apoptosis contributes to the side effects of cancer treatment, and genetic or
pharmacological inhibition of p53 function can increase normal tissue resistance to …

Mitochondria play central roles in cellular metabolism and apoptosis and are a major source
of reactive oxygen species (ROS). We investigated the role of ROS and mitochondria in …

Target motion due to breathing is one of the major obstacles in dose escalation of radiation
therapy to some tumors in the thoracoabdominal region. The development of beam gating or …

Alpha particles are energetic short-range ions whose higher linear energy transfer produces
extreme cytotoxicity. An α-particle-emitting radioimmunoconjugate consisting of a bismuth-…

Image-guided radiation therapy represents a new paradigm in the field of high-precision
radiation medicine. A synthesis of recent technological advances in medical imaging and …

Magnetic biodegradable poly(lactic acid) microspheres that incorporate both magnetite and
the β-emitter 90 Y were prepared. By applying a directional external magnetic field gradient …

Massachusetts docrinology, and thousands of patients were treated annually in the years
1910— 1925. The widespread use of radium compounds in the production ofluminous paints …

Although the biological effects of low-frequency electromagnetic radiation have been
studied since the time of Paracelsus, there is still no consensus on whether these effects are …

The benefits of radiation therapy (RT) as part of a treatment regimen for cancer must be
weighed against the potential risk of harm to the patient and in the pregnant patient, the risk to …