User profiles for R.C. Smart

Robert C. Smart

North Carolina State University
Verified email at ncsu.edu
Cited by 5822

Inhibitory Effect of Curcumin, Chlorogenic Acid, Caffeic Acid, and Ferulic Acid on Tumor Promotion in Mouse Skin by 12-O-Tetradecanoylphorbol-13-acetate

MT Huang, RC Smart, CQ Wong, AH Conney - Cancer research, 1988 - AACR
The effects of topically applied curcumin, chlorogenic acid, caffeic acid, and ferulic acid on
12-O-tetradecanoylphorbol-13-acetate (TPA)-induced epidermal ornithine decarboxylase …

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis

…, DB Dunson, EG Rogan, SG Morham, RC Smart… - Cancer research, 2002 - AACR
Nonsteroidal anti-inflammatory drugs are widely reported to inhibit carcinogenesis in humans
and in rodents. These drugs are believed to act by inhibiting one or both of the known …

Measurement of novel, drinking water-associated PFAS in blood from adults and children in Wilmington, North Carolina

…, K Burdette, J DeWitt, K May, RC Smart… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: From 1980 to 2017, a fluorochemical manufacturing facility discharged wastewater
containing poorly understood per- and polyfluoroalkyl substances (PFAS) to the Cape …

Control of skin cancer by the circadian rhythm

…, CP Selby, WK Kaufmann, RC Smart… - Proceedings of the …, 2011 - National Acad Sciences
Skin cancer is the most common form of cancer in the United States. The main cause of this
cancer is DNA damage induced by the UV component of sunlight. In humans and mice, UV …

CCAAT/enhancer binding protein-β is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling

…, E Sterneck, PF Johnson, RC Smart - Proceedings of the …, 2002 - National Acad Sciences
The basic leucine zipper transcription factor CCAAT/enhancer binding protein-β (C/EBPβ) is
expressed in many cell types, including keratinocytes. C/EBPβ activity can be increased by …

Influence of aging on oral-pharyngeal bolus transit and clearance during swallowing: scintigraphic study

…, DW Shaw, E McKay, RC Smart… - American Journal …, 1994 - journals.physiology.org
The aim of the study was to determine the influence of normal aging on regional transit and
the efficiency of bolus clearance during the oral and pharyngeal phases of swallowing. We …

An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation.

HS Oh, RC Smart - Proceedings of the National Academy of …, 1996 - National Acad Sciences
The hair follicle is a cyclic, self renewing epidermal structure which is thought to be controlled
by signals from the dermal papilla, a specialized cluster of mesenchymal cells within the …

C/EBPβ modulates the early events of keratinocyte differentiation involving growth arrest and keratin 1 and keratin 10 expression

…, E Sterneck, PF Johnson, RC Smart - … and cellular biology, 1999 - Am Soc Microbiol
The epidermis is a stratified squamous epithelium composed primarily of keratinocytes that
become postmitotic and undergo sequential changes in gene expression during terminal …

[HTML][HTML] TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

…, H Sanjo, S Sato, S Akira, RC Smart… - Journal of Biological …, 2006 - ASBMB
Transforming growth factor β-activated kinase 1 (TAK1) functions downstream of inflammatory
cytokines to activate c-Jun N-terminal kinase (JNK) as well as NF-κB in several cell types. …

[HTML][HTML] Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

…, HW Tam, SL Phillips, L Recio, RC Smart - Cell death & …, 2015 - nature.com
LincRNA-p21 is a long noncoding RNA and a transcriptional target of p53 and HIF-1α.
LincRNA-p21 regulates gene expression in cis and trans, mRNA translation, protein stability, the …