Drug discovery for malaria has been transformed in the last 5 years by the discovery of many
new lead compounds identified by phenotypic screening. The process of developing these …

Twenty subjects were randomly assigned to: 1) prophylactic ibuprofen (N= 5)[400 mg TID
initiated 4 h before collection of baseline data and strenuous eccentric exercise bout], 2) …

This book emphasizes the major concepts of both anthropology and the anthropology of
religion and examines religious expression from a cross-cultural perspective while …

Recent studies suggest that endothelin and its receptors may be involved in atherogenesis.
To test this hypothesis, cholesterol-fed hamsters were treated with a selective endothelin …

Monepantel (AAD 1566) is the first compound from the recently discovered amino-acetonitrile
derivative (AAD) class of anthelmintics to be developed for use in sheep. Three dose …

Pediatric Crohn disease is characterized by clinical and endoscopic relapses. The
inflammatory process is considered to be progressive and may lead to strictures, fistulas, and …

Circulating biomarkers are important surrogates for monitoring disease activity in type I Gaucher
disease (GD1). We and others have reported low high-density lipoprotein (HDL) in GD1. …

A series of substituted guanidine derivatives were prepared and evaluated as potent and
selective inhibitors of mitochondrial F 1 F 0 ATP hydrolase. The initial thiourethane derived …

Statins, because of their excellent efficacy and manageable safety profile, represent a key
component in the current armamentarium for the treatment of hypercholesterolemia. …

BACKGROUND: Anti-RNA polymerase III antibodies (anti-RNAP III) have been reported as
potential immune markers of Systemic Sclerosis (SSc). Until now, their clinical use was …