Hypoxia is essential for the development of autoimmune diseases such as rheumatoid arthritis
(RA) and is associated with the expression of reactive oxygen species (ROS), because of …

Background Mitogen-activated protein kinase (MAPK) signaling plays an important role in
inflammatory diseases such as rheumatoid arthritis (RA).The aim of our study was to elucidate …

Hypoxia is essential for the development of autoimmune diseases such as rheumatoid
arthritis (RA) and is associated with the expression of reactive oxygen species (ROS), due to …

Mass spectrometry is a very versatile and important technique in analytical chemistry. From
atomic bombs to Alzheimer’s disease, after a century of improvements and developments …

Objective Increased numbers of tumor-infiltrating lymphocytes (TILs) in high-grade serous
ovarian cancer (HGSC) are associated with improved clinical outcome. Intraepithelial …

The application of single-cell molecular profiling coupled with spatial technologies has
enabled charting cellular heterogeneity in reference tissues and in disease. This new wave of …

Autism spectrum disorder (ASD) is a highly heterogeneous disorder, yet transcriptomic
profiling of bulk brain tissue has identified substantial convergence among dysregulated genes …

Striated muscle is a highly organized structure composed of well-defined anatomical domains
with integrated but distinct assignments. So far, the lack of a direct correlation between …

The application of single cell molecular profiling coupled with spatial technologies has
enabled charting cellular heterogeneity in reference tissues and in disease. This new wave of …

2 Results Spatial Domain Detection: To evaluate the performance of GLaST, we applied it to
a 10x Visium dataset containing SRT measurements of 12 human dorsolateral prefrontal …