Decompressive surgery for the treatment of malignant infarction of the middle cerebral artery (DESTINY) a randomized, controlled trial
E Jüttler, S Schwab, P Schmiedek, A Unterberg… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— Decompressive surgery (hemicraniectomy) for life-threatening
massive cerebral infarction represents a controversial issue in neurocritical care medicine. …
massive cerebral infarction represents a controversial issue in neurocritical care medicine. …
Management of severe traumatic brain injury by decompressive craniectomy
…, L Schürer, A Piepgras, T Paul, P Schmiedek - …, 2000 - journals.lww.com
OBJECTIVE: The beneficial effect of decompressive craniectomy in the treatment of head
trauma patients is controversial. The aim of our study was to assess the value of unilateral …
trauma patients is controversial. The aim of our study was to assess the value of unilateral …
Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1) randomized, double-blind, placebo …
…, NF Kassell, S Mayer, D Ruefenacht, P Schmiedek… - Stroke, 2008 - Am Heart Assoc
Background and Purpose— This randomized, double-blind, placebo-controlled, dose-finding
study assessed efficacy and safety of 1, 5, and 15 mg/h intravenous clazosentan, an …
study assessed efficacy and safety of 1, 5, and 15 mg/h intravenous clazosentan, an …
Outcome after less-invasive decompression of lumbar spinal stenosis: a randomized comparison of unilateral laminotomy, bilateral laminotomy, and laminectomy
…, C Pöckler-Schöniger, J Wöhrle, P Schmiedek - … of Neurosurgery: Spine, 2005 - thejns.org
Object Recently, limited decompression procedures have been proposed in the treatment of
lumbar stenosis. The authors undertook a prospective study to compare the safety and …
lumbar stenosis. The authors undertook a prospective study to compare the safety and …
Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage
…, P Hermann, M Quintel, P Schmiedek… - Critical care …, 2007 - journals.lww.com
Objective: Hypertensive, hypervolemic, hemodilution therapy (triple-H therapy) is a generally
accepted treatment for cerebral vasospasm after subarachnoid hemorrhage. However, the …
accepted treatment for cerebral vasospasm after subarachnoid hemorrhage. However, the …
Intraoperative control of extracranial—intracranial bypass patency by near-infrared indocyanine green videoangiography
J Woitzik, P Horn, P Vajkoczy, P Schmiedek - Journal of neurosurgery, 2005 - thejns.org
Object. Recently, intraoperative fluorescence angiography in which indocyanine green (ICG)
is used as a tracer has been introduced as a novel technique to confirm successful …
is used as a tracer has been introduced as a novel technique to confirm successful …
Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid …
…, C Thome, F Ringel, V Breu, P Schmiedek - Journal of …, 2005 - thejns.org
Objective The goal of this study was to investigate the safety and tolerability of the novel
endothelin A (ET A ) receptor antagonist clazosentan in patients with subarachnoid hemorrhage …
endothelin A (ET A ) receptor antagonist clazosentan in patients with subarachnoid hemorrhage …
Improvement of cerebrovascular reserve capacity by EC-IC arterial bypass surgery in patients with ICA occlusion and hemodynamic cerebral ischemia
P Schmiedek, A Piepgras, G Leinsinger… - Journal of …, 1994 - thejns.org
✓ Since the negative results of the international Bypass Study, extracranial-intracranial (EC-IC)
bypass surgery is infrequently employed in the treatment of patients with cerebral …
bypass surgery is infrequently employed in the treatment of patients with cerebral …
Continuous monitoring of regional cerebral blood flow: experimental and clinical validation of a novel thermal diffusion microprobe
…, C Zappletal, E Klar, L Schilling, P Schmiedek - Journal of …, 2000 - thejns.org
Object. Current clinical neuromonitoring techniques lack adequate surveillance of cerebral
perfusion. In this article, a novel thermal diffusion (TD) microprobe is evaluated for the …
perfusion. In this article, a novel thermal diffusion (TD) microprobe is evaluated for the …
Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage
…, NF Kassell, SA Mayer, D Ruefenacht, P Schmiedek… - Stroke, 2011 - Am Heart Assoc
Background and Purpose— The long-standing concept that delayed cerebral infarction after
aneurysmal subarachnoid hemorrhage results exclusively from large artery vasospasm …
aneurysmal subarachnoid hemorrhage results exclusively from large artery vasospasm …