OBJECTIVE: The serotonin system is believed to play a role in modulating impulsivity and
violence. Previous imaging studies have implicated the anterior cingulate and orbitofrontal …

Background Major depressive disorder is associated with raised peripheral inflammatory
markers. Mounting evidence also suggests that inflammation is involved in suicidal behavior. …

These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

OBJECTIVE: Ketamine is a noncompetitive antagonist at the glutamatergic N-methyl-d-aspartate
(NMDA) receptor that is used in human and animal medicine as an injectable anesthetic…

A number of effective maintenance medication options exist for bipolar disorder (BD) and
these are regarded as the foundation of long-term treatment in BD. However, nonadherence to …

Alterations of serotonin transporters (SERT) are implicated in a large number of psychiatric
conditions. C-(+)-6β-(4-Methylthiophenyl)-1,2,3,5,6α,10β-hexahydropyrrolo[2,1-a]…

The variability in the response to antipsychotic medication in schizophrenia may reflect
between-patient differences in neurobiology. Recent cross-sectional neuroimaging studies …

(–)‐N‐Propyl‐norapomorphine (NPA) is a full dopamine (DA) D 2 receptor agonist and [ 11
C]NPA is a suitable radiotracer to image D 2 receptors configured in a state of high affinity for …

Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of
severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous …

It is a growing concern that outcomes of neuroimaging studies often cannot be replicated.
To counteract this, the magnetic resonance (MR) neuroimaging community has promoted …