For over 40 years, 18 F-FDG has been the dominant PET tracer in neurology, cardiology,
inflammatory diseases, and, most particularly, oncology. Combined with the ability to perform …

This digest highlights recent developments in the field of molecular imaging of cancer using
peptide-based targeting entities. Syntheses of novel radiolabelled prosthetic groups and …

Immune checkpoint inhibitors and related molecules can achieve tumour regression, and
even prolonged survival, for a subset of cancer patients with an otherwise dire prognosis. …

Introduction For many cancers, tumour hypoxia is an adverse prognostic factor, and increases
chemoradiation resistance; its importance in non‐small cell lung cancer ( NSCLC ) is …

Amyloid-β plaques, consisting of aggregated amyloid-β peptides, are one of the
pathological hallmarks of Alzheimer’s disease. Copper complexes formed using positron-emitting …

The synthesis of new bis(thiosemicarbazonato)copper(II) complexes featuring polyamine
substituents via selective transamination reactions is presented. Polyamines of different lengths…

A squaramide ester derivative of desferrioxamine B (H3DFO) that is compatible with aqueous
solvents and does not induce antibody aggregation is used to attach the siderophore to the …

PURPOSE: This study was performed to compare the 2-nitroimidazole derivatives [124I]
IAZA,[18F] FAZA and well known [18F] FMISO in visualization of tumor hypoxia in a mouse …

The use of copper radioisotopes in cancer diagnosis and radionuclide therapy is possible
using chelators that are capable of binding CuII with sufficient stability in vivo to provide high …

Two new bifunctional tris(hydroxypyridinone) (THP) chelators designed specifically for rapid
labeling with 68 Ga have been synthesized, each with pendant isothiocyanate groups and …