Purpose: Preclinical studies have shown good anti-cancer activity following targeting of a
polymer bearing doxorubicin with galactosamine (PK2) to the liver. The present phase I study …

Objective Functional neuroimaging studies have shown that experimentally induced acute
pain is processed within at least 2 parallel networks of brain structures collectively known as …

High-resolution three-dimensional (3-D) positron emission tomography (PET) scanners with
high count rate performance, such as the quad-high density avalanche chamber (HIDAC), …

Methodology for PET system modeling using image-space techniques in the expectation
maximization (EM) algorithm is presented. The approach, applicable to both list-mode data and …

Galactose-targeted delivery of macromolecules and drug conjugates to asialoglycoprotein
receptor (ASGPR) positive cells has been widely documented in animals, although targeting …

This study aimed to investigate the relationship between outcome following cochlear implantation
and auditory cortical activation. It also studied the effects of length of implant use and …

Purpose: A fully human monoclonal antibody to anti–α v integrins (CNTO 95) has been shown
to inhibit angiogenesis and tumor growth in preclinical studies. We assessed the safety …

Iterative image reconstruction methods such as ordered-subset expectation maximization (OSEM)
are widely used in PET. Reconstructions via OSEM are however reported to be biased …

The impact of positron emission tomography (PET) on radiation therapy is held back by
poor methods of defining functional volumes of interest. Many new software tools are being …

BACKGROUND AND PURPOSE: In HIV infected patients, MRI cannot reliably differentiate
between central nervous system (CNS) lymphoma and non-malignant CNS lesions, …