User profiles for Peter J. Hudson
Peter HudsonPenn State University Verified email at psu.edu Cited by 33419 |
Engineered antibody fragments and the rise of single domains
P Holliger, PJ Hudson - Nature biotechnology, 2005 - nature.com
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals. …
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals. …
Is a healthy ecosystem one that is rich in parasites?
Historically, the role of parasites in ecosystem functioning has been considered trivial
because a cursory examination reveals that their relative biomass is low compared with that of …
because a cursory examination reveals that their relative biomass is low compared with that of …
Prevention of population cycles by parasite removal
The regular cyclic fluctuations in vertebrate numbers have intrigued scientists for more than
70 years, and yet the cause of such cycles has not been clearly demonstrated. Red grouse …
70 years, and yet the cause of such cycles has not been clearly demonstrated. Red grouse …
[HTML][HTML] Pathways to zoonotic spillover
Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon. …
human, presents a global public health burden but is a poorly understood phenomenon. …
[BOOK][B] The ecology of wildlife diseases
The majority of living organisms are parasitic in one form or another, be they a virus invading
a sea coral, a tapeworm within the guts of your dog, a cuckoo chick in a reed warbler's nest …
a sea coral, a tapeworm within the guts of your dog, a cuckoo chick in a reed warbler's nest …
Engineered antibodies
PJ Hudson, C Souriau - Nature medicine, 2003 - nature.com
Engineered antibodies now represent over 30% of biopharmaceuticals in clinical trials, as
highlighted by recent approvals from the US Food and Drug Administration. Recombinant …
highlighted by recent approvals from the US Food and Drug Administration. Recombinant …
Epidemic dynamics at the human-animal interface
Few infectious diseases are entirely human-specific: Most human pathogens also circulate
in animals or else originated in nonhuman hosts. Influenza, plague, and trypanosomiasis are …
in animals or else originated in nonhuman hosts. Influenza, plague, and trypanosomiasis are …
Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer
Many animal species are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection and could act as reservoirs; however, transmission in free-living …
infection and could act as reservoirs; however, transmission in free-living …
Do parasites make prey vulnerable to predation? Red grouse and parasites
1. An extensive post-mortem survey of grouse revealed that birds killed by predators in spring
and summer had significantly greater burdens of the caecal nematode Trichostrongylus …
and summer had significantly greater burdens of the caecal nematode Trichostrongylus …
Ecological dynamics of emerging bat virus spillover
RK Plowright, P Eby, PJ Hudson… - … of the royal …, 2015 - royalsocietypublishing.org
Viruses that originate in bats may be the most notorious emerging zoonoses that spill over
from wildlife into domestic animals and humans. Understanding how these infections filter …
from wildlife into domestic animals and humans. Understanding how these infections filter …