User profiles for Peter J. Hudson

Peter Hudson

Penn State University
Verified email at psu.edu
Cited by 33419

Engineered antibody fragments and the rise of single domains

P Holliger, PJ Hudson - Nature biotechnology, 2005 - nature.com
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals. …

Is a healthy ecosystem one that is rich in parasites?

PJ Hudson, AP Dobson, KD Lafferty - Trends in ecology & evolution, 2006 - cell.com
Historically, the role of parasites in ecosystem functioning has been considered trivial
because a cursory examination reveals that their relative biomass is low compared with that of …

Prevention of population cycles by parasite removal

PJ Hudson, AP Dobson, D Newborn - science, 1998 - science.org
The regular cyclic fluctuations in vertebrate numbers have intrigued scientists for more than
70 years, and yet the cause of such cycles has not been clearly demonstrated. Red grouse …

[HTML][HTML] Pathways to zoonotic spillover

…, CR Parrish, H McCallum, PJ Hudson… - Nature Reviews …, 2017 - nature.com
Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon. …

[BOOK][B] The ecology of wildlife diseases

PJ Hudson, A Rizzoli, BT Grenfell, H Heesterbeek… - 2002 - researchgate.net
The majority of living organisms are parasitic in one form or another, be they a virus invading
a sea coral, a tapeworm within the guts of your dog, a cuckoo chick in a reed warbler's nest …

Engineered antibodies

PJ Hudson, C Souriau - Nature medicine, 2003 - nature.com
Engineered antibodies now represent over 30% of biopharmaceuticals in clinical trials, as
highlighted by recent approvals from the US Food and Drug Administration. Recombinant …

Epidemic dynamics at the human-animal interface

…, VE Pitzer, JRC Pulliam, AP Dobson, PJ Hudson… - science, 2009 - science.org
Few infectious diseases are entirely human-specific: Most human pathogens also circulate
in animals or else originated in nonhuman hosts. Influenza, plague, and trypanosomiasis are …

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

…, JJ Davis, JM Musser, PJ Hudson… - Proceedings of the …, 2022 - National Acad Sciences
Many animal species are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection and could act as reservoirs; however, transmission in free-living …

Do parasites make prey vulnerable to predation? Red grouse and parasites

PJ Hudson, AP Dobson, D Newborn - Journal of animal ecology, 1992 - JSTOR
1. An extensive post-mortem survey of grouse revealed that birds killed by predators in spring
and summer had significantly greater burdens of the caecal nematode Trichostrongylus …

Ecological dynamics of emerging bat virus spillover

RK Plowright, P Eby, PJ Hudson… - … of the royal …, 2015 - royalsocietypublishing.org
Viruses that originate in bats may be the most notorious emerging zoonoses that spill over
from wildlife into domestic animals and humans. Understanding how these infections filter …