User profiles for Peter D. Katsikis

Peter Katsikis

Professor, Department of Immunology, Erasmus University Medical Center
Verified email at erasmusmc.nl
Cited by 12504

Convalescent plasma for COVID-19. A randomized clinical trial

…, P Boekhorst, FH Swaneveld, PD Katsikis… - MEDRxiv, 2020 - medrxiv.org
Structured abstract for full paper Background After recovery from COVID-19, most patients
have anti-SARS-CoV-2 neutralizing antibodies. Their convalescent plasma could be an …

[PDF][PDF] The PD-1/PD-L1-checkpoint restrains T cell immunity in tumor-draining lymph nodes

…, L Boon, A Moyaart, YM Mueller, PD Katsikis… - Cancer cell, 2020 - cell.com
PD-1/PD-L1-checkpoint blockade therapy is generally thought to relieve tumor cell-mediated
suppression in the tumor microenvironment but PD-L1 is also expressed on non-tumor …

Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals.

PD Katsikis, ES Wunderlich, CA Smith… - The Journal of …, 1995 - rupress.org
Apoptosis (programmed cell death) of T lymphocytes has been proposed as a mechanism
which plays an important role in the pathogenesis of human immunodeficiency virus (HIV) …

[HTML][HTML] The cytokine network of acute HIV infection: a promising target for vaccines and therapy to reduce viral set-point?

PD Katsikis, YM Mueller, F Villinger - PLoS pathogens, 2011 - journals.plos.org
Cytokines play a central role in the pathogenesis of many diseases, including HIV infection.
However, the role of the cytokine network in early HIV infection is only now starting to be …

Interleukin‐10 inhibition of the progression of established collagen‐induced arthritis

M Walmsley, PD Katsikis, E Abney… - … : Official Journal of …, 1996 - Wiley Online Library
Objective. Interleukin‐10 (IL‐10) is a potent inhibitor of the proinflammatory cytokines, including
tumor necrosis factor α and IL‐1, which are considered important in the pathogenesis of …

In vivo detection and imaging of phosphatidylserine expression during programmed cell death

FG Blankenberg, PD Katsikis, JF Tait… - Proceedings of the …, 1998 - National Acad Sciences
One of the earliest events in programmed cell death is the externalization of phosphatidylserine,
a membrane phospholipid normally restricted to the inner leaflet of the lipid bilayer. …

Immunoregulatory role of interleukin 10 in rheumatoid arthritis.

PD Katsikis, CQ Chu, FM Brennan, RN Maini… - The Journal of …, 1994 - rupress.org
The presence and the role of interleukin 10 (IL-10), a potent cytokine synthesis inhibitory
factor and antiinflammatory cytokine, were investigated in rheumatoid arthritis (RA). The …

The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling

…, JA Fraietta, EJ Wherry, M Turner, PD Katsikis - Nature …, 2013 - nature.com
We found upregulation of expression of the microRNA miR-155 in primary effector and effector
memory CD8 + T cells, but low miR-155 expression in naive and central memory cells. …

[HTML][HTML] Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

…, B Rockx, NMA Okba, PD Katsikis… - Nature …, 2021 - nature.com
In a randomized clinical trial of 86 hospitalized COVID-19 patients comparing standard care
to treatment with 300mL convalescent plasma containing high titers of neutralizing SARS-…

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

…, M Roederer, E Gostick, PD Katsikis… - Blood, The Journal …, 2011 - ashpublications.org
A highly complex network of coinhibitory and costimulatory receptors regulates the outcome
of virus-specific CD8 + T-cell responses. Here, we report on the expression patterns of …