The ability to locate nerve injury and ensuing neuroinflammation would have tremendous
clinical value for improving both the diagnosis and subsequent management of patients …

The purpose of this study was to assess safety, biodistribution, and radiation dosimetry in
humans for the highly selective σ-1 receptor PET agent 18 F-6-(3-fluoropropyl)-3-(2-(azepan-1-…

Chronic sciatica is a major cause of disability worldwide, but accurate diagnosis of the
causative pathology remains challenging. In this report, the feasibility of an 18 F-FDG PET/MRI …

Background The ability to accurately diagnose and objectively localize pain generators in
chronic pain sufferers remains a major clinical challenge since assessment relies on …

Purpose Sigma-1 receptors (S1Rs) play an important role in many neurological disorders.
Simultaneous positron emission tomography (PET)/magnetic resonance imaging (MRI) with …

Objective The goal of this study is to demonstrate the feasibility of simultaneous [ 18 F]-fluorodeoxyglucose
(FDG) positron emission tomography (PET) and magnetic resonance imaging …

Introduction: Chronic pelvic pain is a highly prevalent pain condition among women, but
identifying the exact cause of pelvic pain remains a significant diagnostic challenge. In this study…

Background Over the past couple of decades, a number of centers in the brain have been
identified as important sites of nociceptive processing and are collectively known as the ‘pain …

Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition affecting
millions of patients worldwide. However, no specific diagnosis is currently available to …

178 Objectives: Accurately identifying nociceptive sources of low back pain has remained to
be a great diagnostic challenge despite its pressing need due to the high prevalence and …