Dopamine, serotonin, and norepinephrine are essential for neurotransmission in the mammalian
system. These three neurotransmitters have been the focus of considerable research …

BACKGROUND: The dopamine transporter (DAT) is known to be a key regulator of dopamine,
and recent studies of genetics, treatment, and imaging have highlighted the role of DAT in …

Increasing evidence indicates that dopamine (DA) transporter density declines in
Parkinson's disease (PD). 2β‐Carbomethoxy‐3β‐(4‐fluorophenyl)‐n‐(1‐iodoprop‐1‐en‐3‐yl) …

Cocaine is a potent stimulant of the mammalian central nervous system. Its reinforcing and
stimulant properties have been associated with its propensity to bind to monoamine …

Cocaine is a stimulant drug with a high abuse liability. Although it inhibits several monamine
transporters in the mammalian brain, its primary mechanism of action has been ascribed to …

Cocaine is a potent central nervous system stimulant with severe addiction liability. Its
reinforcing and stimulant properties derive from inhibition of monoamine transport systems, in …

The dopamine transporter (DAT), located presynaptically on dopamine neurons, provides a
marker for certain neurological diseases. In particular, the DAT is depleted in Parkinson's …

Increasing evidence suggests that the dopamine transporter is situated almost exclusively on
dopamine neurons. Accordingly, it is an valuable marker for Parkinson's disease and other …

Methylphenidate (Ritalin) binds stereoselectively and enantioselectively to the dopamine
transporter (DAT) and inhibits dopamine reuptake with in vitro and in vivo potency similar to …

2n5 ^ ci both N7 and N9 isomers be in hand. 11 In the absence of one of the isomers, the
assignment cannot be unambiguously made by these means and Osterman et al. 12 have …