The overexpression of Bombesin (BBS) receptors on a variety of human cancers make them
interesting targets for tumor imaging and therapy. Analogues of the neuropeptide BBS have …

The study aim was to assess the safety, biodistribution, tissue kinetics, and tumor uptake of
the 99m Tc-labeled neurotensin (NT) analog NT-XI. Methods: Four patients presenting ductal …

A new radiolabeled bombesin analogue, [ 99m Tc(I)-PADA-AVA]bombesin (7-14), was
synthesized and in vitro and in vivo characterized. High affinity and rapid internalization were …

The rapid degradation of neurotensin (NT) limits its clinical use in cancer imaging and therapy.
Thus, a new NT(8–13) pseudopeptide, NT-VIII, was synthesized. Some changes were …

The potential utility of neurotensin (NT) in cancer diagnosis and therapy is limited by its
rapid degradation. New stabilized analogues were synthesized, labeled with [ 99m Tc] and …

Purpose: The L1 cell adhesion protein is overexpressed in tumors, such as neuroblastomas,
renal cell carcinomas, ovarian carcinomas, and endometrial carcinomas, and represents a …

INTRODUCTION: Bombesin, a neuropeptide with potential for breast and prostate tumor
targeting, is rapidly metabolized in vivo, and as a result, uptake in tumor xenografts in mice is …

Radiolabeled bombesin (BBS) analogues are promising pharmaceuticals for imaging of
cancer cells expressing gastrin-releasing peptide receptors (GRPR). However, most of the …

Brain edema significantly contributes to the clinical course of human brain tumor patients.
There is evidence that an enlargement of the extracellular space (ECS) is involved in the …

Purpose Neurotensin (NT) and its high affinity receptor (NTR1) are involved in several
neoplastic processes. Thus, NT-based radiopharmaceuticals are potential tracers for targeted …