Background CSF and PET biomarkers of amyloid β and tau accurately detect Alzheimer's
disease pathology, but the invasiveness, high cost, and poor availability of these detection …

The quantification of phosphorylated tau in biofluids, either cerebrospinal fluid (CSF) or
plasma, has shown great promise in detecting Alzheimer’s disease (AD) pathophysiology. Tau …

Whilst cerebrospinal fluid (CSF) and positron emission tomography (PET) biomarkers for
amyloid-β (Aβ) and tau pathologies are accurate for the diagnosis of Alzheimer’s disease (AD), …

Compelling experimental evidence suggests that microglial activation is involved in the spread
of tau tangles over the neocortex in Alzheimer’s disease (AD). We tested the hypothesis …

Neuroanatomical differences attributable to aging and gender have been well documented,
and these differences may be associated with differences in behaviors and cognitive …

Importance Glial fibrillary acidic protein (GFAP) is a marker of reactive astrogliosis that
increases in the cerebrospinal fluid (CSF) and blood of individuals with Alzheimer disease (AD). …

Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape emergent …

The purpose of this paper is to establish single-participant white matter atlases based on
diffusion tensor imaging. As one of the applications of the atlas, automated brain segmentation …

Structural delineation and assignment are the fundamental steps in understanding the anatomy
of the human brain. The white matter has been structurally defined in the past only at its …

An unresolved question for the understanding of Alzheimer’s disease (AD) pathophysiology
is why a significant percentage of amyloid-β (Aβ)-positive cognitively unimpaired (CU) …