ERBB receptor tyrosine kinases and cellular radiation responses

…, JN Contessa, G Lammering, G Amorino, PS Lin - Oncogene, 2003 - nature.com
Ionizing radiation induces in autocrine growth-regulated carcinoma and malignant glioma
cells powerful cytoprotective responses that confer relative resistance to consecutive radiation …

Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen

JK Leach, G Van Tuyle, PS Lin, R Schmidt-Ullrich… - Cancer research, 2001 - AACR
Transient generation of reactive oxygen or nitrogen (ROS/RNS), detected with
dihydrodichlorofluoroscein by fluorescence microscopy, occurs within minutes of exposing cells to …

The efficacy of several irrigating solutions for endodontics: a scanning electron microscopic study

…, M Goldman, JH Kronman, PS Lin - Oral Surgery, Oral …, 1981 - Elsevier
The perforated irrigation needle was used to test a high-volume (20 cc) final flush of prepared
root canals. Three solutions: TEGO 1 percent, NaOCl 5.25 percent, and REDTA were …

[PDF][PDF] Molecular mechanisms of radiation‐induced accelerated repopulation

…, K Valerie, DB Reardon, G Bowers, PS Lin - Radiation oncology …, 1999 - academia.edu
Accelerated proliferation (or repopulation) after repeated exposure of cells to ionizing
radiation represents a response of acute reacting normal tissues and tumors. Evidence for …

Neural stem cells: implications for the conventional radiotherapy of central nervous system malignancies

IJ Barani, SH Benedict, PS Lin - International Journal of Radiation …, 2007 - Elsevier
Advances in basic neuroscience related to neural stem cells and their malignant counterparts
are challenging traditional models of central nervous system tumorigenesis and intrinsic …

Radiation-induced activation of a common variant of EGFR confers enhanced radioresistance

G Lammering, K Valerie, PS Lin, TH Hewit… - Radiotherapy and …, 2004 - Elsevier
BACKGROUND AND PURPOSE: The type-III EGFR variant (EGFRvIII) is known to promote
enhanced tumorigenicity. We have previously defined the importance of EGFRvIII in cellular …

Neural stem cell-preserving external-beam radiotherapy of central nervous system malignancies

…, Y Wu, TD Chung, WC Broaddus, PS Lin - International Journal of …, 2007 - Elsevier
Purpose: Recent discoveries have implicated neural stem cells (NSC) as the source of
plasticity and repair in the mature mammalian brain. Treatment-induced NSC dysfunction may …

Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

T Zhou, K Akopiants, S Mohapatra, PS Lin, K Valerie… - DNA repair, 2009 - Elsevier
Although tyrosyl-DNA phosphodiesterase (TDP1) is capable of removing blocked 3′ termini
from DNA double-strand break ends, it is uncertain whether this activity plays a role in …

Modulation in the radiosensitivity of MCF-7 human breast carcinoma cells by 17B-estradiol and tamoxifen

DE Wazer, OF Tercilla, PS Lin… - The British journal of …, 1989 - birpublications.org
Colony-forming ability after exposure to ionizing irradiation was compared for proliferating
hormone response MCF-7 breast carcinoma cells and cells whose growth was inhibited by …

Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity

…, TH Hewit, M Holmes, K Valerie, W Hawkins, PS Lin… - Clinical cancer …, 2004 - AACR
Purpose: The commonly expressed variant epidermal growth factor receptor (EGFR), the
type III EGFR variant (EGFRvIII), functions as an oncoprotein promoting neoplastic …