Production and supply of α-particle–emitting radionuclides for targeted α-therapy
…, M Pruszyński, O Valzdorf, P Causey… - Journal of nuclear …, 2021 - Soc Nuclear Med
Encouraging results from targeted α-therapy have received significant attention from academia
and industry. However, the limited availability of suitable radionuclides has hampered …
and industry. However, the limited availability of suitable radionuclides has hampered …
232Th-Spallation-Produced 225Ac with Reduced 227Ac Content
…, R Perron, V Radchenko, S Zeisler, P Causey… - Inorganic …, 2020 - ACS Publications
Recent clinical results have demonstrated remarkable treatment responses of late-stage
cancer patients when treated with alpha-emitting radionuclides such as actinium-225 ( 225 Ac). …
cancer patients when treated with alpha-emitting radionuclides such as actinium-225 ( 225 Ac). …
Synthesis and Evaluation of a Macrocyclic Actinium‐225 Chelator, Quality Control and In Vivo Evaluation of 225Ac‐crown‐αMSH Peptide
…, R Perron, D Gendron, P Causey… - … A European Journal, 2020 - Wiley Online Library
Targeted alpha‐therapy (TAT) has great potential for treating a broad range of late‐stage
cancers by delivering a focused and lethal radiation dose to tumors. Actinium‐225 ( 225 Ac) is …
cancers by delivering a focused and lethal radiation dose to tumors. Actinium‐225 ( 225 Ac) is …
Red manganese phthalocyanines from highly hindered hexadecaalkoxyphthalocyanines
CC Leznoff, LS Black, A Hiebert, PW Causey… - Inorganica chimica …, 2006 - Elsevier
Highly hindered magnesium and metal-free green 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecaneopentoxyphthalocyanine
and 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-…
and 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-…
Synthesis, characterization, and assessment of cytotoxic properties of a series of titanocene dichloride derivatives
PW Causey, MC Baird, SPC Cole - Organometallics, 2004 - ACS Publications
A series of 15 water-soluble titanocene dichloride derivatives containing alkylammonium
groups pendant to one (monocationic complexes) or both (dicationic complexes) …
groups pendant to one (monocationic complexes) or both (dicationic complexes) …
Construction of a thorium/actinium generator at the Canadian Nuclear Laboratories
R Perron, D Gendron, PW Causey - Applied Radiation and Isotopes, 2020 - Elsevier
Targeted Alpha Therapy (TAT) has demonstrated considerable promise in the treatment of a
range of cancers in both preclinical and, more recently clinical research. In particular, work …
range of cancers in both preclinical and, more recently clinical research. In particular, work …
Self-radiolysis of tritiated water. 1. A comparison of the effects of 60 Co γ-rays and tritium β-particles on water and aqueous solutions at room temperature
…, S Sanguanmith, J Meesungnoen, P Causey… - RSC …, 2013 - pubs.rsc.org
Monte Carlo simulations were used to investigate the chemistry of pure water and aqueous
solutions after irradiation with different kinds of radiation: tritium β-rays and high-energy …
solutions after irradiation with different kinds of radiation: tritium β-rays and high-energy …
Synthesis and screening of mono-and di-aryl technetium and rhenium metallocarboranes. A new class of probes for the estrogen receptor
PW Causey, TR Besanger… - Journal of medicinal …, 2008 - ACS Publications
A series of mono and diaryl rhenium(I)-carborane derivatives were prepared using microwave
heating and screened for their affinity for two isoforms of the estrogen receptor (ER). The …
heating and screened for their affinity for two isoforms of the estrogen receptor (ER). The …
[HTML][HTML] A suitable time point for quantifying the radiochemical purity of 225Ac-labeled radiopharmaceuticals
Background As 225 Ac-labeled radiopharmaceuticals continue to show promise as targeted
alpha therapeutics, there is a growing need to standardize quality control (QC) testing …
alpha therapeutics, there is a growing need to standardize quality control (QC) testing …
Microwave-Assisted Synthesis of 3,1,2- and 2,1,8-Re(I) and 99mTc(I)−Metallocarborane Complexes
AEC Green, PW Causey, AS Louie… - Inorganic …, 2006 - ACS Publications
Microwave heating was used to prepare η 5 -rhenium carborane complexes in aqueous
reaction media. For carboranes bearing sterically demanding substituents, isomerization of the …
reaction media. For carboranes bearing sterically demanding substituents, isomerization of the …