User profiles for Patrick Breheny

Patrick Breheny

Professor of Biostatistics, University of Iowa
Verified email at uiowa.edu
Cited by 6043

[HTML][HTML] Coordinate descent algorithms for nonconvex penalized regression, with applications to biological feature selection

P Breheny, J Huang - The annals of applied statistics, 2011 - ncbi.nlm.nih.gov
A number of variable selection methods have been proposed involving nonconvex penalty
functions. These methods, which include the smoothly clipped absolute deviation (SCAD) …

[PDF][PDF] Visualization of regression models using visreg.

P Breheny, W Burchett - R J., 2017 - Citeseer
Regression models allow one to isolate the relationship between the outcome and an explanatory
variable while the other variables are held constant. Here, we introduce an R package…

The group exponential lasso for bi-level variable selection

P Breheny - Biometrics, 2015 - academic.oup.com
In many applications, covariates possess a grouping structure that can be incorporated into
the analysis to select important groups as well as important members of those groups. One …

[HTML][HTML] A selective review of group selection in high-dimensional models

J Huang, P Breheny, S Ma - Statistical science: a review journal of …, 2012 - ncbi.nlm.nih.gov
Grouping structures arise naturally in many statistical modeling problems. Several methods
have been proposed for variable selection that respect grouping structure in variables. …

Group descent algorithms for nonconvex penalized linear and logistic regression models with grouped predictors

P Breheny, J Huang - Statistics and computing, 2015 - Springer
Penalized regression is an attractive framework for variable selection problems. Often,
variables possess a grouping structure, and the relevant selection problem is that of selecting …

[HTML][HTML] Penalized methods for bi-level variable selection

P Breheny, J Huang - Statistics and its interface, 2009 - ncbi.nlm.nih.gov
In many applications, covariates possess a grouping structure that can be incorporated into
the analysis to select important groups as well as important members of those groups. This …

Surface sensing in Vibrio parahaemolyticus triggers a programme of gene expression that promotes colonization and virulence

…, RJ Kustusch, PJ Breheny… - Molecular …, 2011 - Wiley Online Library
Vibrio parahaemolyticus senses surfaces via impeded rotation of its polar flagellum. We
have exploited this surface‐sensing mechanism to trick the organism into thinking it is on a …

Multivariate predictors of music perception and appraisal by adult cochlear implant users

…, J Oleson, JF Knutson, P Breheny… - Journal of the …, 2008 - thieme-connect.com
The research examined whether performance by adult cochlear implant recipients on a variety
of recognition and appraisal tests derived from real-world music could be predicted from …

68Ga-DOTATOC imaging of neuroendocrine tumors: a systematic review and metaanalysis

MM Graham, X Gu, T Ginader, P Breheny… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68 Ga-DOTATOC, a somatostatin receptor–targeted ligand, has been used clinically in Europe
over the past decade for imaging neuroendocrine tumors (NETs). It appears to be quite …

[PDF][PDF] Cancer cells resist mechanical destruction in circulation via RhoA/actomyosin-dependent mechano-adaptation

…, G Burke, L Rhodes, M Vanneste, P Breheny… - Cell reports, 2020 - cell.com
During metastasis, cancer cells are exposed to potentially destructive hemodynamic forces
including fluid shear stress (FSS) while en route to distant sites. However, prior work …