This review focuses on the systemic complications of acromegaly. Mortality in this disease is
increased mostly because of cardiovascular and respiratory diseases, although currently …

Importance Although plenty of data exist regarding clinical manifestations, course, case
fatality rate, and risk factors associated with mortality in severe coronavirus disease 2019 (COVID…

Patients with Cushing’s disease (CD) mainly die because of cardiovascular accidents. The
aim of this study was to evaluate whether patients with CD still have increased cardiovascular …

Impaired cardiovascular function has recently been demonstrated to potentially reduce life
expectancy both in GH deficiency and excess. Experimental and clinical studies have …

Objectives: Obesity can alter the thyroid hormone status as a result of a dysregulated
endocrine loop between the hypothalamo-pituitary unit and adipose tissue. The adipocytokine …

The effects of a 12- to 24-month treatment with depot long-acting octreotide (OCT-LAR) on
hormone profile, tumor mass, and clinical symptoms were reported in 36 patients with active …

Clinical features and natural history of coronavirus disease 2019 (COVID-19) differ widely
among different countries and during different phases of the pandemia. Here, we aimed to …

Obesity and thyroid diseases are common disorders in the general population and they
frequently occur in single individuals. Alongside a chance association, a direct relationship …

Ghrelin is a gastric hormone that exerts a stimulatory effect on appetite and fat accumulation.
Ser(3) octanoylation is regarded as a prerequisite for ghrelin biological activity, although …

Increased mortality from cardiovascular diseases has been reported in acromegaly. Our
objective was to evaluate the impact of glucose tolerance abnormalities and/or systemic …