Purpose: To compare the outcomes associated with modifications in three consecutive
protocols employed by the Italian Co-Operative Group for Neuroblastoma (ICGNB) in …

A national cooperative project on rare paediatric tumours (the TREP project) was launched
in 2000 in Italy, with a view to improving the clinical management and the basic research on …

Purpose: To identify the prognostic factors, treatment, and outcome of children affected by
renal cell carcinoma (RCC). Patients and Methods: The series included 41 patients (18 males …

BACKGROUND: Nasopharyngeal carcinoma (NPC) is very rare in childhood. It differs from
its adult counterpart in the prevalence of the nonkeratinizing, undifferentiated subtype and by …

BACKGROUND Pleuropulmonary blastoma (PPB) is a rare and aggressive malignant tumor
that affects children and adults. This neoplasm is histologically characterized by primitive …

Background Pleuropulmonary blastoma (PPB) is an aggressive embryonal malignancy
presenting in early childhood, presumably arising from pleuropulmonary mesenchyme. The …

Background Teratomas demonstrate a benign clinical behavior, however they may recur with
malignant components or as teratoma, and in a small group of patients prognosis could be …

BACKGROUND: The outcome of patients with non-extremity synovial sarcoma (SS) is generally
worse than that of patients with limb tumours. METHODS: The present study analysed a …

The fact that anthracyclines are cardiotoxic seriously narrows their therapeutic index in
cancer therapy. The cardiotoxic risk increases with the cumulative dose and may lead to …

BACKGROUND: In many types of cancer, the survival rates are reported to be less favorable
for adolescents compared with younger children. To investigate whether this is true for …