Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

We identified rare coding variants associated with Alzheimer's disease in a three-stage case–control
study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole-…

The Rey-Osterrieth complex figure test (ROCF) is a neuropsychological test extensively
used in clinical practice to investigate visuospatial constructional functions, visuographic …

Background In March 2020, the World Health Organization declared a global pandemic due
to the novel coronavirus SARS-CoV-2 and several governments planned a national …

Background/Aims: Sleep disturbances are common in the elderly and in persons with cognitive
decline. The aim of this study was to describe frequency and characteristics of insomnia, …

The aim of the present study is to compare brain atrophy with hypometabolism as preclinical
markers of Alzheimer's disease (AD) by studying presymptomatic individuals from families …

Whole-brain functional magnetic resonance imaging (MRI) was used to examine the neural
substrates of internally (endogenous) and externally (exogenous) induced covert shifts of …

Introduction Previous studies showed that quarantine for pandemic diseases is associated
with several psychological and medical effects. The consequences of quarantine for COVID-…

Background Alzheimer's disease is a common debilitating dementia with known heritability,
for which 20 late onset susceptibility loci have been identified, but more remain to be …

Background Late‐onset Alzheimer's disease (AD) is heritable with 20 genes showing
genome‐wide association in the International Genomics of Alzheimer's Project (IGAP). To identify …