Radioactive labeling of antibody: a simple and efficient method

…, D Lanteigne, MA Davis, TW Griffin, PW Doherty - Science, 1983 - science.org
A simple and efficient method of covalently coupling the strong chelator
diethylenetriaminepentaacetic acid to proteins was developed for radiolabeling immunoglobulin G …

[PDF][PDF] Two-dimensional filtering of SPECT images using the Metz and Wiener filters

MA King, RB Schwinger, PW Doherty… - Journal of Nuclear …, 1984 - Soc Nuclear Med
METHODS Two restoration filters that adapt to the images being processed were investigated,
for use as two-dimensional window functions for preprocessing SPECT images and in …

A Wiener filter for nuclear medicine images

MA King, PW Doherty, RB Schwinger… - Medical …, 1983 - Wiley Online Library
To improve the quality of digital nuclear medicine images, we have developed a new
implementation of the Wiener restoration filter. The Wiener filter uses as its optimality criterion the …

DTPA-coupled antibodies labeled with yttrium-90.

DJ Hnatowich, F Virzi, PW Doherty - Journal of nuclear medicine …, 1985 - europepmc.org
Yttrium-90 has been described as one of the best radionuclides for tumor therapy when
chelated to tumor-associated antibodies. This evaluation is based on the superior properties of …

Cardiac damage produced by direct current countershock applied to the heart

PW Doherty, PR McLaughlin, M Billingham… - The American journal of …, 1979 - Elsevier
This study examined the pathophysiology of the myocardial damage produced by direct current
shock over a dose range of 10 to 90 wattseconds, applied directly to the heart in 26 dogs…

[PDF][PDF] Indium-111-labeled autologous platelets for location of vascular thrombi in humans

DA Goodwin, JT Bushberg, PW Doherty… - Journal of Nuclear …, 1978 - Soc Nuclear Med
METHOD Twenty-two patients suspected of having either arterial or venous clots were studied.
A modification (17) of the method of Thakur et al.(10) was used. The main steps included …

Detection and quantitation of myocardial infarction in vivo using transmission computed tomography.

PW Doherty, MJ Lipton, WH Berninger… - Circulation, 1981 - Am Heart Assoc
In vivo studies were performed on 28 dogs to evaluate the usefulness of transmission computed
tomography (CT) in the detection and quantitation of experimentally induced myocardial …

[PDF][PDF] Patient biodistribution of intraperitoneally administered yttrium-90-labeled antibody

…, M Gionet, T Griffin, PW Doherty… - Journal of nuclear …, 1988 - Soc Nuclear Med
MATERIALS AND METhODS The anti-ovarian tumor antibody OC-l25 was developed by
Bast et al. by immunizing BALB/c mice with human epithelial cells obtained originally from a …

[PDF][PDF] Pharmacokinetics of an indium-111-labeled monoclonal antibody in cancer patients

…, JA Mattis, D Shealy, PW Doherty - Journal of nuclear …, 1985 - Soc Nuclear Med
… Shealy, and PW Doherty … King MA, Doherty PW: A computer program for re construction
of images from a scanning gamma camera. … Schwinger RB, King MA, Doherty PW, et …

[PDF][PDF] Interactive visual optimization of SPECT prereconstruction filtering

…, BC Penney, RB Schwinger, PW Doherty - Journal of Nuclear …, 1987 - Soc Nuclear Med
Doherty … King MA, Doherty PW, Schwinger RB, et al. A Wie … King MA, Schwinger RB,
Doherty PW, et al. Two dimensional filtering ofSPECF images using the Metz …