User profiles for P. Henson

Henson, P

Verified email at njhealth.org
Cited by 83955

Phagocyte recognition of cells undergoing apoptosis

J Savill, V Fadok, P Henson, C Haslett - Immunology today, 1993 - cell.com
A key feature of apoptosis is that cells undergoing this programmed form of death are
recognized by phagocytes and irgested while still intact, protecting tizsues from the potentially …

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

…, SC Frasch, ML Warner, PM Henson - Cell Death & …, 1998 - nature.com
Exposure of phosphatidylserine on the outer leaflet of the plasma membrane is a surface
change common to many apoptotic cells. Normally restricted to the inner leaflet, …

[PDF][PDF] Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins.

PM Henson, RB Johnston - The Journal of clinical …, 1987 - Am Soc Clin Investig
In circumstancesof acute injury to tissues of the body, it is currently popular to incriminate
byproducts of oxygen metabolism as the ultimate injurious agents. A disparate array ofcon-…

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

…, JJ Cohen, DL Bratton, PM Henson - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
During normal tissue remodeling, macrophages remove unwanted cells, including those that
have undergone programmed cell death, or apoptosis. This widespread process extends to …

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta …

…, PW Freed, JY Westcott, PM Henson - The Journal of …, 1998 - Am Soc Clin Investig
… apoptotic cells (P 0.0001), IL-10 was decreased significantly compared with LPS treatment
alone (P … compared with macrophages treated with both LPS and opsonized apoptotic cells (P

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

…, JE Henson, MJ Walport, PM Henson… - The Journal of …, 1989 - Am Soc Clin Investig
Mechanisms governing the normal resolution processes of inflammation are poorly understood,
yet their elucidation may lead to a greater understanding of the pathogenesis of chronic …

[PDF][PDF] Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte

…, DL Bratton, PA Oldenborg, M Michalak, PM Henson - Cell, 2005 - cell.com
… Statistical analysis and p values were carried out using the JMP statistical program (SAS
Institute, Cary, North Carolina). The Tukey-Kramer and Dunnett’s parametrical tests were used …

A receptor for phosphatidylserine-specific clearance of apoptotic cells

…, DM Rose, A Pearson, RAB Ezekewitz, PM Henson - Nature, 2000 - nature.com
… Konowal for generation of the cDNA library from J774 cells; P. Taylor for assistance with
bioinformatics; R. Schlegel and P. Williamson for critical comments; and D. Voelker for technical …

LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS: THE ROLE OF IGE, BASOPHILS, AND A PLATELET-ACTIVATING FACTOR

J Benveniste, PM Henson, CG Cochrane - The Journal of experimental …, 1972 - rupress.org
We have studied the leukocyte-dependent mechanism of histamine release (LDHR) from
rabbit platelets, a complement-independent mechanism which has been implicated in the …

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

…, B Ghebrehiwet, VA Fadok, PM Henson - The Journal of …, 2001 - rupress.org
Removal of apoptotic cells is essential for maintenance of tissue homeostasis, organogenesis,
remodeling, development, and maintenance of the immune system, protection against …