User profiles for P. Danny Allen

PD Allen

Professor of Anaesthesia, Emeritus, Harvard Medical School
Verified email at hms.harvard.edu
Cited by 19443

Computerized nailfold video capillaroscopy--a new tool for assessment of Raynaud's phenomenon.

ME Anderson, PD Allen, T Moore, V Hillier… - The Journal of …, 2005 - jrheum.org
OBJECTIVE: To develop a computer based nailfold video capillaroscopy system with
enhanced image quality and to assess its disease-subgroup resolving power in patients with …

Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca2+ release channel/ryanodine receptors

…, D Bichet, M El Ayeb, H Rochat, PD Allen… - FEBS …, 2000 - Wiley Online Library
Maurocalcine is a novel toxin isolated from the venom of the chactid scorpion Scorpio
maurus palmatus. It is a 33‐mer basic peptide cross‐linked by three disulfide bridges, which …

Imaging DNA damage repair in vivo after 177Lu-DOTATATE therapy

E O'Neill, V Kersemans, PD Allen… - Journal of Nuclear …, 2020 - Soc Nuclear Med
… Bart Cornelissen, Michael Mosley, Sean Smart, P. Danny Allen, and Veerle Kersemans were
supported by CRUK through the CRUK/MRC Oxford Institute for Radiation Oncology. Julia …

Detecting reduced bone mineral density from dental radiographs using statistical shape models

PD Allen, J Graham, DJJ Farnell… - IEEE transactions on …, 2007 - ieeexplore.ieee.org
We describe a novel method of estimating reduced bone mineral density (BMD) from dental
panoramic tomograms (DPTs), which show the entire mandible. Careful expert width …

[HTML][HTML] Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours

…, MJ Mosley, V Kersemans, GM Dias, PD Allen… - Nuclear Medicine and …, 2019 - Elsevier
While radiolabelled antibodies have found great utility as PET and SPECT imaging agents
in oncological investigations, a notable shortcoming of these agents is their propensity to …

89Zr-anti-γH2AX-TAT but not 18F-FDG Allows Early Monitoring of Response to Chemotherapy in a Mouse Model of Pancreatic Ductal Adenocarcinoma

…, MJ Mosley, LC Bravo, V Kersemans, PD Allen… - Clinical Cancer …, 2017 - AACR
Purpose: Late-stage, unresectable pancreatic ductal adenocarcinoma (PDAC) is largely
resistant to chemotherapy and consequently has a very poor 5-year survival rate of <5%. The …

MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform

…, J Thompson, M Hill, PD Allen… - The British journal of …, 2017 - academic.oup.com
Objective: Neuroblastoma has one of the lowest survival rates of all childhood cancers,
despite the use of intensive treatment regimens. Preclinical models of neuroblastoma are …

Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer

…, C Kartsonaki, V Kersemans, PD Allen… - Journal of Nuclear …, 2014 - Soc Nuclear Med
A prominent feature of many human cancers is oncogene-driven activation of the DNA
damage response (DDR) during early tumorigenesis. It has been shown previously that …

Recruitment of a myeloid cell subset (CD11b/Gr1mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis

…, TT Tapmeier, JH Im, Y Cao, J Beech, D Allen… - Hepatology, 2013 - journals.lww.com
Liver metastasis from colorectal cancer is a leading cause of cancer mortality. Myeloid cells
play pivotal roles in the metastatic process, but their prometastatic functions in liver …

[HTML][HTML] Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates

…, A Jefferson, N Ruparelia, AM Akhtar, J Xie, D Allen… - Theranostics, 2015 - ncbi.nlm.nih.gov
Angiogenesis is an essential component of tumour growth and, consequently, an important
target both therapeutically and diagnostically. The cell adhesion molecule α v β 3 integrin is …