Positron emission tomography (PET) is now regularly used in the diagnosis and staging of
cancer. These uses and its ability to monitor treatment response would be aided by the …

Early global deprivation of institutionalized children may result in persistent specific cognitive
and behavioral deficits. In order to examine brain dysfunction underlying these deficits, we …

Serotonin content, serotonin uptake sites, and serotonin receptor binding measured in animal
studies are all higher in the developing brain, compared with adult values, and decline …

OBJECTIVES. We previously reported that children who were subjected to early socioemotional
deprivation in Romanian orphanages showed glucose hypometabolism in limbic and …

The high energetic costs of human brain development have been hypothesized to explain
distinctive human traits, including exceptionally slow and protracted preadult growth. Although …

Based on reports of increased platelet serotonin in 30 to 50% of autistic subjects, abnormal
serotonergic neurotransmission may be important in the pathogenesis of autism. However, …

BACKGROUND The objective of this study was to compare coronary flow reserve (CFR) as
a measure of vascular integrity in asymptomatic middle-aged men with family history of …

Although it has been believed that brown adipose tissue (BAT) depots disappear shortly
after the perinatal period in humans, PET imaging using the glucose analog 18 F-FDG has …

The role of serotonin in prenatal and postnatal brain development is well documented in the
animal literature. In earlier studies using positron emission tomography (PET) with the tracer …

SPM is a powerful technique for the comparison of functional imaging data sets among groups
of patients. While this technique has been widely applied in studies of adults, it has rarely …