Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy

…, P Verdijk, JH Van Krieken, OC Boerman… - Nature …, 2005 - nature.com
The success of cellular therapies will depend in part on accurate delivery of cells to target
organs. In dendritic cell therapy, in particular, delivery and subsequent migration of cells to …

Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes

…, FHM Corstens, OC Boerman - … of Pharmacology and …, 2000 - ASPET
Sterically stabilized liposomes are considered promising carriers of therapeutic agents because
they can facilitate controlled release of the drugs, thereby reducing drug-related toxicity …

Peritoneal carcinomatosis of colorectal origin: incidence and current treatment strategies

MJ Koppe, OC Boerman, WJG Oyen… - Annals of …, 2006 - journals.lww.com
Objective: To review the literature with regard to the incidence and prognostic significance
of peritoneal seeding during surgery for primary colorectal cancer (CRC), the incidence of …

Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

…, GNP Van Muijen, SP Strijk, TJ Ruers, OC Boerman… - Cancer research, 2003 - AACR
Dendritic cells are the professional antigen-presenting cells of the immune system. To induce
an effective immune response, these cells should not only express high levels of MHC and …

Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase

FA Wagener, A Eggert, OC Boerman… - Blood, The Journal …, 2001 - ashpublications.org
Various pathologic conditions, such as hemorrhage, hemolysis and cell injury, are characterized
by the release of large amounts of heme. Recently, it was demonstrated that heme …

A novel method of 18F radiolabeling for PET

…, P Laverman, CH Chang, OC Boerman… - Journal of nuclear …, 2009 - Soc Nuclear Med
Small biomolecules are typically radiolabeled with 18 F by binding it to a carbon atom, a
process that usually is designed uniquely for each new molecule and requires several steps …

Tumor Targeting with Radiolabeled αvβ3 Integrin Binding Peptides in a Nude Mouse Model

…, H Boonstra, FH Corstens, OC Boerman - Cancer research, 2002 - AACR
The α v β 3 integrin is expressed on proliferating endothelial cells such as those present in
growing tumors, as well as on tumor cells of various origin. Tumor-induced angiogenesis can …

Complete remission of experimental arthritis by joint targeting of glucocorticoids with long‐circulating liposomes

…, JPA Wagenaar‐Hilbers, OC Boerman… - … : Official Journal of …, 2003 - Wiley Online Library
Objective To increase the therapeutic activity of glucocorticoids in experimental arthritis by
encapsulation in long‐circulating polyethylene glycol liposomes, which have shown the ability …

Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients

…, BM Schulte, D Benitez-Ribas, OC Boerman… - Cancer research, 2013 - AACR
Vaccination against cancer by using dendritic cells has for more than a decade been based
on dendritic cells generated ex vivo from monocytes or CD34 + progenitors. Here, we report …

Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection

P Laverman, MG Carstens, OC Boerman… - … of Pharmacology and …, 2001 - ASPET
Previously, we showed that long-circulating polyethylene glycol (PEG)-liposomes are cleared
rapidly from the circulation when injected repeatedly in the same animal. In this article, we …