User profiles for Oluwaseun Johnson-Akeju
 | Oluwaseun AkejuMGH Verified email at mgh.harvard.edu Cited by 5744 |
Effects of ketamine infusion on breathing and encephalography in spontaneously breathing ICU patients
…, S Chamadia, O Johnson-Akeju… - Journal of Intensive …, 2023 - journals.sagepub.com
Background Preclinical studies suggest that ketamine stimulates breathing. We investigated
whether adding a ketamine infusion at low and high doses to propofol sedation improves …
whether adding a ketamine infusion at low and high doses to propofol sedation improves …
Sound and light levels in intensive care units in a large urban hospital in the United States
…, BT Thompson, O Johnson-Akeju… - Chronobiology …, 2023 - Taylor & Francis
Intensive care units (ICUs) may disrupt sleep. Quantitative ICU studies of concurrent and
continuous sound and light levels and timings remain sparse in part due to the lack of ICU …
continuous sound and light levels and timings remain sparse in part due to the lack of ICU …
Sleep and circadian biomarkers of postoperative delirium: protocol for a prospective, observational cohort study
Surgical patients over 70 experience postoperative delirium (POD) complications in up to 50%
of procedures. Sleep/circadian disruption has emerged as a potential risk factor for POD …
of procedures. Sleep/circadian disruption has emerged as a potential risk factor for POD …
Sleep disturbance and incident Alzheimer's disease: A UK Biobank study of 502,538 middle‐aged to older participants: Biomarkers (non‐neuroimaging): Alzheimer's …
Background Recent cross‐sectional studies have suggested a link between sleep disturbance
and worse neurocognitive function. We hypothesized that sleep disturbance traits (short/…
and worse neurocognitive function. We hypothesized that sleep disturbance traits (short/…
The Pandemic Brain: neuroinflammation in healthy, non-infected individuals during the COVID-19 pandemic
Background The impact of COVID-19 on human health extends beyond the morbidity and
death toll directly caused by the SARS-CoV-2 virus. In fact, accumulating evidence indicates a …
death toll directly caused by the SARS-CoV-2 virus. In fact, accumulating evidence indicates a …
Circadian disturbances, risk for postoperative delirium and conversion to dementia
…, FAJL Scheer, O Johnson‐Akeju… - Alzheimer's & …, 2023 - Wiley Online Library
Background Delirium is one of the most common complications in older adults after surgery.
Circadian rest‐activity rhythms are known to be disrupted with age, and among individuals …
Circadian rest‐activity rhythms are known to be disrupted with age, and among individuals …
The Pandemic Brain: neuroinflammation in healthy, non-infected individuals during the COVID-19 pandemic (preprint)
SummaryO_ST_ABSBackgroundC_ST_ABSThe impact of COVID-19 on human health
extends beyond the morbidity and death toll directly caused by the SARS-CoV-2 virus. In fact, …
extends beyond the morbidity and death toll directly caused by the SARS-CoV-2 virus. In fact, …
Depression symptoms and risk for delirium during hospitalization and after surgery
Background Delirium is an acute neuropsychiatric disorder associated with increased risks
of Alzheimer’s disease (AD) and death; it is characterized by acute confusion commonly after …
of Alzheimer’s disease (AD) and death; it is characterized by acute confusion commonly after …
767: EPILEPTIFORM ABNORMALITIES ARE ASSOCIATED WITH INCREASED MORTALITY IN ADULT ECMO PATIENTS
…, WL Zheng, K Shelton, O Johnson-Akeju… - Critical Care …, 2020 - journals.lww.com
Methods: Retrospective review of a prospective ECMO registry in a university hospital
between 2011-2019 (490 adult subjects). Subjects who had decreased level of consciousness …
between 2011-2019 (490 adult subjects). Subjects who had decreased level of consciousness …