Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis

…, M Brauner, P Soler, J Marchal, O Raguin… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Idiopathic pulmonary fibrosis (IPF) is characterized by an uncontrolled accumulation and
activation of lung fibroblasts. A modulation of fibroblast activation has been observed in various …

Evaluation of 99mTc-UBI 29-41 scintigraphy for specific detection of experimental Staphylococcus aureus prosthetic joint infections

…, A Meulemans, JM Vrigneaud, O Raguin… - European Journal of …, 2007 - Springer
Purpose 99m Tc-UBI 29-41 (UBI), an antimicrobial peptide, specifically targets bacteria. We
tested the ability of UBI to discriminate between infected and uninfected prosthetic joints …

99mTc-Annexin-V Functional Imaging of Luminal Thrombus Activity in Abdominal Aortic Aneurysms

…, M Coutard, F Rouzet, O Raguin… - … , and vascular biology, 2006 - Am Heart Assoc
Background— The mural thrombus of abdominal aortic aneurysms (AAA) is involved in
aneurysm progression via several interdependent biological processes including platelet …

DOTAGA-Trastuzumab. A New Antibody Conjugate Targeting HER2/Neu Antigen for Diagnostic Purposes

M Moreau, O Raguin, JM Vrigneaud… - Bioconjugate …, 2012 - ACS Publications
Improved bifunctional chelating agents (BFC) are required for indium-111 radiolabeling of
monoclonal antibodies (mAbs) under mild conditions to yield stable, target-specific agents. 2,2…

Novel neurotensin analogues for radioisotope targeting to neurotensin receptor-positive tumors

…, C Rosant, V Maes, J Abdelhak, O Raguin… - Bioconjugate …, 2009 - ACS Publications
The increased expression of the neurotensin (NT) receptor NTS1 by different cancer cells,
such as pancreatic adenocarcinoma and ductal breast cancer cells, as compared to normal …

Unraveling the interaction between carboxylesterase 1c and the antibody–drug conjugate SYD985: improved translational PK/PD by using Ces1c knockout mice

…, MMC van der Lee, F Bichat, O Raguin… - Molecular cancer …, 2018 - AACR
Carboxylesterase 1c (CES1c) is responsible for linker-drug instability and poor pharmacokinetics
(PK) of several antibody–drug conjugates (ADC) in mice, but not in monkeys or humans…

Assessment of PET tracer uptake in hormone-independent and hormone-dependent xenograft prostate cancer mouse models

D Kukuk, G Reischl, O Raguin, S Wiehr… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The pharmacokinetics of 18 F-fluorodeoxythymidine (FLT), 18 F-FDG, 11 C-choline, and 18
F-fluoroethylcholine (FEC) in 2 hormone-independent (PC-3, DU145) and 2 hormone-…

[HTML][HTML] Association of serum lactate with outcome after out-of-hospital cardiac arrest treated with therapeutic hypothermia

…, R Plattier, M Nefzaoui, H Hyvernat, O Raguin… - PLoS …, 2017 - journals.plos.org
Aims Lactate reflects hypoxic insult in many conditions and is considered as a prognosis
factor. But, after cardiac arrest, its interest is still debated. Our study aimed to assess the …

BODIPY: A highly versatile platform for the design of bimodal imaging probes

…, C Bernhard, V Goncalves, O Raguin… - … A European Journal, 2015 - Wiley Online Library
In molecular imaging, multimodal imaging agents can provide complementary information,
for improving the accuracy of disease diagnosis or enhancing patient management. In …

Comparison of presumed cardiac and respiratory causes of out-of-hospital cardiac arrest

…, F Cattet, R Plattier, M Nefzaoui, H Hyvernat, O Raguin… - Resuscitation, 2018 - Elsevier
Aims of the study Most interventional and observational studies include cardiac arrest from
cardiac origin. However, an increasing proportion of cardiac arrest results from an extra-…