The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin.
K Takei, O Mundigl, L Daniell, P De Camilli - The Journal of cell biology, 1996 - rupress.org
Strong evidence implicates clathrin-coated vesicles and endosome-like vacuoles in the
reformation of synaptic vesicles after exocytosis, and it is generally assumed that these vacuoles …
reformation of synaptic vesicles after exocytosis, and it is generally assumed that these vacuoles …
A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.
C David, PS McPherson, O Mundigl… - Proceedings of the …, 1996 - National Acad Sciences
Amphiphysin, a major autoantigen in paraneoplastic Stiff-Man syndrome, is an SH3 domain-containing
neuronal protein, concentrated in nerve terminals. Here, we demonstrate a …
neuronal protein, concentrated in nerve terminals. Here, we demonstrate a …
Preclinical Activity of the Type II CD20 Antibody GA101 (Obinutuzumab) Compared with Rituximab and Ofatumumab In Vitro and in Xenograft Models
S Herter, F Herting, O Mundigl, I Waldhauer… - Molecular cancer …, 2013 - AACR
We report the first preclinical in vitro and in vivo comparison of GA101 (obinutuzumab), a novel
glycoengineered type II CD20 monoclonal antibody, with rituximab and ofatumumab, the …
glycoengineered type II CD20 monoclonal antibody, with rituximab and ofatumumab, the …
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies
G Niederfellner, A Lammens, O Mundigl… - Blood, The Journal …, 2011 - ashpublications.org
CD20 is a cell-surface marker of normal and malignant B cells. Rituximab, a monoclonal
antibody targeting CD20, has improved the treatment of malignant lymphomas. Therapeutic …
antibody targeting CD20, has improved the treatment of malignant lymphomas. Therapeutic …
Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin
K Kraszewski, O Mundigl, L Daniell… - Journal of …, 1995 - Soc Neuroscience
Antibodies directed against the lumenal domain of synaptotagmin I conjugated to CY3 (CY3-Syt1-Abs)
and video microscopy were used to study the dynamics of synaptic vesicles in …
and video microscopy were used to study the dynamics of synaptic vesicles in …
Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
A Schoch, H Kettenberger, O Mundigl… - Proceedings of the …, 2015 - National Acad Sciences
Here, we investigated the influence of the variable fragment (Fv) of IgG antibodies on the
binding to the neonatal Fc receptor (FcRn) as well as on FcRn-dependent pharmacokinetics (…
binding to the neonatal Fc receptor (FcRn) as well as on FcRn-dependent pharmacokinetics (…
Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells.
Cellubrevin is a member of the synaptobrevin/VAMP family of SNAREs, which has a broad
tissue distribution. In fibroblastic cells it is concentrated in the vesicles which recycle …
tissue distribution. In fibroblastic cells it is concentrated in the vesicles which recycle …
[HTML][HTML] The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy
…, L Spycher, W Zago, R Barbour, O Mundigl… - Acta …, 2021 - Springer
Various post-translationally modified (PTM) proteoforms of alpha-synuclein (aSyn)—including
C-terminally truncated (CTT) and Serine 129 phosphorylated (Ser129-p) aSyn—…
C-terminally truncated (CTT) and Serine 129 phosphorylated (Ser129-p) aSyn—…
Bispecific digoxigenin-binding antibodies for targeted payload delivery
…, W Scheuer, E Hoffmann, O Mundigl… - Proceedings of the …, 2011 - National Acad Sciences
Bispecific antibodies that bind cell-surface targets as well as digoxigenin (Dig) were generated
for targeted payload delivery. Targeting moieties are IgGs that bind the tumor antigens …
for targeted payload delivery. Targeting moieties are IgGs that bind the tumor antigens …
Expression and targeting of the tight junction protein CLDN1 in CLDN1‐negative human breast tumor cells
T Hoevel, R Macek, O Mundigl… - Journal of cellular …, 2002 - Wiley Online Library
Claudins and occludin constitute the major transmembrane proteins of tight junctions (TJs).
We have previously identified the human homologue of the murine Cldn1, CLDN1 (SEMP1) …
We have previously identified the human homologue of the murine Cldn1, CLDN1 (SEMP1) …