Background Accumulating evidence links brown adipose tissue (BAT) to increased cold-induced
energy expenditure (CIEE) and regulation of lipid metabolism in humans. BAT has also …

Obesity is associated with increasing cardiometabolic morbidity and mortality rates worldwide.
Not everyone with obesity, however, develops metabolic complications. Brown adipose …

We introduce multiple-organ objective segmentation (MOOSE) software that generates
subject-specific, multiorgan segmentation using data-centric artificial intelligence principles to …

Due to its high metabolic activity, brown adipose tissue (BAT) has become a promising target
for the development of novel treatment concepts for metabolic disease. Despite several …

Introduction Brown adipose tissue (BAT) is suggested to exhibit a sexual dimorphism and
thus contributes to the observed sex differences in cardiometabolic risk observed between …

99m Tc-PHC-102 is a 99m Tc-labeled derivative of acetazolamide, a high-affinity small
organic ligand of carbonic anhydrase IX (CAIX). 99m Tc-PHC-102 has previously shown …

Cold-induced activation of thermogenesis modulates energy metabolism, but the role of
humoral mediators is not completely understood. We aimed to investigate the role of parathyroid …

Introduction Obesity affects a rising proportion of the population and is an important risk
factor for unfavorable outcomes in viral disease including severe acute respiratory syndrome …

Background Interstitial lung disease (ILD) is a common manifestation of idiopathic inflammatory
myopathies (IIM) and a substantial contributor to hospitalisation, increased morbidity, …

Introduction Bile acid signaling has been suggested to promote BAT activity in various
experimental models. However, little is known if and how physiologic bile acid metabolism is …