Revised Manuscript Received June 2, 1993® abstract: VW-Methyl-L-arginine (l-NMA) is one
of the most commonly used inhibitors of the nitric oxide synthases (NOS). Results reported …

·N=O synthase catalyzes the oxidation of one of the two chemically equivalent guanido
nitrogens of L-arginine to nitric oxide (·N=O). N G -Methyl-L-arginine has been previously …

… A-Methyl-L-arginine (lNMA) has beenshown to function as a slow, partially uncoupled alternate
substrate and mechanismbased inhibitor of the inducible NOS [Olken, N. M., & Marietta, . …

TV^ Methyl-L-arginine has recently been shown to inactivate the inducible murine macrophage
nitric oxide ('NO) synthase (Olken, NM; Rusche, KM; Richards,. K.; Marietta,. A. Biochem. …

This laboratory previously expressed cDNAs encoding rabbit liver cytochrome P450 2E1. (the
ethanol-inducible isoform) and the corresponding protein lacking amino acids 3-29, a …

We have designed and synthesized two radioiodinated analogs of
hexadecylphosphocholine in order to evaluate their tumor imaging potential. 12-(m[ 125 I]iodophenyl)dodecyl …

NM-294 was synthesized as previously described (4). Purity and proof of structure were
determined by proton nuclear mag netic resonance, infrared analysis, elemental analysis and …

… I would like to thank my parents, Phyllis and Delbert Olken, and my sisters, Wendy and
Robin Olken, for their kindness and understanding. I would tike to thank Bill and Mary Hendrix, …

BACKGROUND The Chronic Respiratory Questionnaire (CRQ) and the St George’s
Respiratory Questionnaire (SGRQ) are the two most widely used quality of life questionnaires in …

From a societal perspective long-term clinical trials or follow-up studies should preferably
not only include an evaluation of the health effect for the patient, but also an economic …