11C-acetate PET imaging of prostate cancer

N Oyama, H Akino, H Kanamaru, Y Suzuki… - Journal of Nuclear …, 2002 - Soc Nuclear Med
11 C-Acetate can act as a probe of tissue metabolism through entry into catabolic or anabolic
metabolic pathways as mediated by acetyl–coenzyme A. The uptake of 11 C-acetate in …

11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse

N Oyama, TR Miller, F Dehdashti… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Patients with rising prostate-specific antigen (PSA) levels after definitive local therapy of
prostate carcinoma present a diagnostic dilemma. A local recurrence would be amenable to …

18F-fluoroacetate: a potential acetate analog for prostate tumor imaging—in vivo evaluation of 18F-fluoroacetate versus 11C-acetate

DE Ponde, CS Dence, N Oyama, J Kim… - Journal of nuclear …, 2007 - Soc Nuclear Med
PET with 11 C-acetate ( 11 C-ACE) has a high sensitivity for detection of prostate cancer and
several other cancers that are poorly detected with 18 F-FDG. However, the short half-life (…

The Increased Accumulation of [18F]Fluorodeoxyglucose in Untreated Prostate Cancer

N Oyama, H Akino, Y Suzuki… - Japanese journal of …, 1999 - academic.oup.com
Background: To evaluate the clinical usefulness of [ 18 F]fluorodeoxyglucose positron
emission tomography (FDG-PET) compared with histopathological grading, clinical stage and …

Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent Cu-diacetyl-bis(N 4-methylthiosemicarbazone) (Cu-ATSM) in tumor …

A Obata, E Yoshimi, A Waki, JS Lewis, N Oyama… - Annals of nuclear …, 2001 - Springer
The retention mechanism of the novel imaging/radiotherapeutic agent, Cu-diacetyl-bis(N 4 -methylthiosemicarbazone)
(Cu-ATSM) in tumor cells was clarified in comparison with that in …

[HTML][HTML] Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy …

Y Yoshii, T Furukawa, N Oyama, Y Hasegawa… - PloS one, 2013 - journals.plos.org
Fatty acid synthase (FASN) expression is elevated in several cancers, and this over-expression
is associated with poor prognosis. Inhibitors of FASN, such as orlistat, reportedly show …

Development of secondary-fuel injection technology for energy reduction in the iron ore sintering process

N Oyama, Y Iwami, T Yamamoto, S Machida… - ISIJ …, 2011 - jstage.jst.go.jp
The technology was put into commercial operation at Keihin No. 1 sinter plant in January 2009
and stable operation has continued up to the present. As a result, the energy efficiency in …

Prognostic value of 2-deoxy-2-[F-18] fluoro-D-glucose positron emission tomography imaging for patients with prostate cancer

N Oyama, H Akino, Y Suzuki, H Kanamaru… - Molecular Imaging & …, 2002 - Elsevier
Purpose: The purpose of this study was to investigate the prognostic value of measuring
glucose metabolism of primary prostate cancer lesions, using 2-Deoxy-2-[F-18]Fluoro-D-…

Radiolabeled Cu-ATSM as a novel indicator of overreduced intracellular state due to mitochondrial dysfunction: studies with mitochondrial DNA-less ρ0 cells and …

…, Y Kiyono, T Mori, H Yoshii, N Oyama… - Nuclear medicine and …, 2012 - Elsevier
OBJECTIVES: Radiolabeled Cu-diacetyl-bis (N 4 -methylthiosemicarbazone) ( ⁎ Cu-ATSM),
including 60/62/64 Cu-ATSM, is a potential imaging agent of hypoxic tumors for positron …

Optimization of coke breeze segregation in sintering bed under high pisolite ore ratio

S Machida, T Higuchi, N Oyama, H Sato, K Takeda… - ISIJ …, 2009 - jstage.jst.go.jp
3) To control the coke segregation in the sintering bed, Magnetic Braking Feeder (MBF) was
introduced, and the operating conditions were investigated with the laboratory charging …