A novel CYP11B2-specific imaging agent for detection of unilateral subtypes of primary aldosteronism

…, M Naruse, WF Young Jr, N Kobashi… - The Journal of …, 2016 - academic.oup.com
Context: Although adrenal vein sampling is the standard method to distinguish unilateral from
bilateral forms of primary aldosteronism, it is an invasive and technically difficult procedure…

[HTML][HTML] Radiation dosimetry and efficacy of an 89Zr/225Ac-labeled humanized anti-MUC5AC antibody

N Nakata, N Kobashi, Y Okumura, M Sato… - Nuclear Medicine and …, 2022 - Elsevier
Introduction Theranostic applications are currently difficult to achieve owing to the limited
evaluation of suitable chelators for therapeutic nuclides, such as 225 Ac and 227 Th. With a …

Novel Benzofurans with 99mTc Complexes as Probes for Imaging Cerebral β-Amyloid Plaques

M Ono, Y Fuchi, T Fuchigami, N Kobashi… - ACS Medicinal …, 2010 - ACS Publications
Two novel benzofuran derivatives coupled with 99m Tc complexes were tested as probes
for imaging cerebral β-amyloid plaques using single photon emission tomography. Although …

Synthesis and characterization of novel phenylindoles as potential probes for imaging of β-amyloid plaques in the brain

H Watanabe, M Ono, M Haratake, N Kobashi… - Bioorganic & medicinal …, 2010 - Elsevier
We synthesized a novel series of phenylindole (PI) derivatives and evaluated their
biological activities as probes for imaging Aβ plaques in vivo. The affinity for Aβ plaques was …

Synthesis and biological evaluation of radioiodinated quinacrine-based derivatives for SPECT imaging of Aβ plaques

T Fuchigami, N Kobashi, M Haratake… - European Journal of …, 2013 - Elsevier
The aim of the present study was to characterize the binding property of quinacrine-based
acridine derivatives for Aβ plaques and to evaluate this series of compounds as Aβ imaging …

Development of radioiodinated acridine derivatives for in vivo imaging of prion deposits in the brain

M Kawasaki, T Fuchigami, N Kobashi… - Bioorganic & Medicinal …, 2017 - Elsevier
Prion diseases are caused by deposition of abnormal prion protein aggregates (PrP Sc ) in
the central nervous system. This study aimed to develop in vivo imaging probes that can …

The thymidine phosphorylase imaging agent 123I-IIMU predicts the efficacy of capecitabine

N Kobashi, H Matsumoto, S Zhao, S Meike… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Recently, companion diagnostics with nuclear medicine techniques have been anticipated
as more suitable means than biopsy for predicting treatment efficacy. The anticancer effect of …

[PDF][PDF] NAOSITE: Nagasaki University's Academic Output SITE

H Watanabe, M Ono, M Haratake, N Kobashi… - Bioorganic & medicinal …, 2010 - core.ac.uk
We synthesized a novel series of phenylindole (PI) derivatives and evaluated their
biological activities as probes for imaging Aβ plaques in vivo. The affinity for Aβ plaques was …

Comparison of trans-1-amino-3-[18 F] fluorocyclobutanecarboxylic acid (anti-[18 F] FACBC) accumulation in lymph node prostate cancer metastasis and …

M Kanagawa, Y Doi, S Oka, R Kobayashi… - Nuclear medicine and …, 2014 - Elsevier
Introduction Trans-1-amino-3-[ 18 F]fluorocyclobutanecarboxylic acid (anti-[ 18 F]FACBC) is
a positron emission tomography (PET) tracer used to visualize prostate cancer (PCa). In this …

SNMMI NEWSLINE

C Kratochwil, FL Giesel, M Stefanova, M Benešova… - Soc Nuclear Med
… 1276 The Thymidine Phosphorylase Imaging Agent 123I-IIMU Predicts the Efficacy of
Capecitabine Nobuya Kobashi, Hiroki Matsumoto, Songji Zhao, Shunsuke Meike, Yuki Okumura, …